Real World Clinical Outcomes Using a Novel Directional Lead from a Multicenter Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: In this report, initial real-world outcomes using a directional lead with a Deep Brain Stimulation (DBS) system capable of multiple independent current source control…Subthalamic Nucleus of Luys: A review. What has evolved since 1865?
Objective: The review provides detailed material about the Subthalamic Nucleus of Luys, including pathophisiolgy, hystorical notes about Luys, embryology, anatomy, principal afferents and efferents pathways, as…Bilateral Globus pallidus internus deep brain stimulation as rescue therapy for ineffective subthalamic stimulation
Objective: The subthalamic nucleus (STN) and the globus pallidus internus (GPi) are the main targets of deep brain stimulation surgery (DBS) for patients with advanced…DBS for PD in Albania
Objective: DBS: surgical procedure of choice for PD. Albanian experience. Background: Parkinson disease (PD) : the decrease of dopamine’s levels because of nigro – striatal…Quantitative study of subthalamic ERG potassium channels in parkinsonian discharges
Objective: This study describes the role of the subthalamic ERG Potassium (ERG K+) ion channel conductance in cellular excitability in subthalamic nucleus (STN) neurons towards…Translation of a subject-specific stereotaxic platform to a large animal deep brain stimulation research models
Objective: To evaluate the feasibility and accuracy of applying the commercially-available, FHC STarFix platform system for direct targeting of deep brain stimulation electrodes in a…Online determination of the STN “sweet spot” based on beta-power measured with directional macro-contacts of the final DBS lead
Objective: Microelectrode recordings are the standard procedure for intraoperative, electrophysiological mapping of the STN[1]. We investigated a novel methodology to detect the STN sweet spot…Assessment of Neuropsychological Outcomes Using a New Multiple Source, Constant- Current Rechargeable Deep Brain Stimulation System for the Treatment of Parkinson’s Disease – INTREPID Study
Objective: To evaluate neuropsychological outcomes in subjects participating in the INTREPID randomized controlled trial (RCT). Background: Neuropsychological evaluation in the context of Deep Brain Stimulation…Development of an unsupervised analysis pipeline for human microelectrode recordings
Objective: Our aim is to develop computational tools that can assist clinical decision in Deep Brain Stimulation (DBS) for Parkinson's disease (PD) using intraoperative microelectrode…Effects of Directional Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s disease
Objective: To assess if a horizontal current steering in the subthalamic nucleus (STN) by directional deep brain stimulation (dDBS) offers clinical advantages compared to conventional…
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