Development of an unsupervised analysis pipeline for human microelectrode recordings
Objective: Our aim is to develop computational tools that can assist clinical decision in Deep Brain Stimulation (DBS) for Parkinson's disease (PD) using intraoperative microelectrode…Effects of Directional Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s disease
Objective: To assess if a horizontal current steering in the subthalamic nucleus (STN) by directional deep brain stimulation (dDBS) offers clinical advantages compared to conventional…MRI based Volumetric analysis of the sub-thalamic and red nuclei in Advanced Parkinson’s disease- an institutional study
Objective: •To evaluate volume of Sub thalamic and Red nuclei on 3T MRI and its 3D reconstruction and its possible correlation with the disease progression in…Interleaved deep brain stimulation for dyskinesia management in Parkinson’s disease
Objective: To evaluate the clinical effects of using interleaving stimulation to simultaneously treat Parkinson’s disease (PD) symptoms and dyskinesia by the generation of two symptom-specific…Changing for a rechargeable neurostimulator in Parkinson’s disease patients: safety and feasibility
Objective: This study aimed to determine the feasibility and safety of the replacement of non-rechargeable implanted pulse generator (IPG) by rechargeable ones. Background: DBS of…Diagnosis and management strategies used in series of Parkinson’s disease patients who experienced subthalamic nucleus deep brain stimulation induced mood elevation
Objective: To describe the diagnosis and management of deep brain stimulation-induced elevated mood states. Background: Deep brain stimulation (DBS) is an FDA-approved surgical treatment option…Is Microelectrode Recording mandatory for Deep Brain Stimulation in Parkinson’s disease?
Objective: To find whether microelectrode recording (MER) is mandatory for deep brain stimulation (DBS) in Parkinson’s disease. Background: DBS is traditionally done using MER guidance.…Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms
Objective: Using opto-activation of cortical interneurons, we aimed at mimicking the cortical effects of deep brain stimulation of the subthalamic nucleus (STN-DBS) to reproduce its…Impact of subthalamic deep brain stimulation on sensorimotor and motor cortical oscillatory activity in free-moving hemiparkinsonian rats
Objective: The effect of STN DBS on the spectral power of oscillatory activity in the classic frequency bands in the motor cortex (MCtx) and sensorimotor…What can predict short and long-term outcome of bilateral Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s disease?
Objective: To define preoperative predictive factors of short- and long-term motor outcome from a large cohort of consecutive Parkinson’s Disease (PD) patients operated on with…
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