Translation of a subject-specific stereotaxic platform to a large animal deep brain stimulation research models
Objective: To evaluate the feasibility and accuracy of applying the commercially-available, FHC STarFix platform system for direct targeting of deep brain stimulation electrodes in a…Online determination of the STN “sweet spot” based on beta-power measured with directional macro-contacts of the final DBS lead
Objective: Microelectrode recordings are the standard procedure for intraoperative, electrophysiological mapping of the STN[1]. We investigated a novel methodology to detect the STN sweet spot…Assessment of Neuropsychological Outcomes Using a New Multiple Source, Constant- Current Rechargeable Deep Brain Stimulation System for the Treatment of Parkinson’s Disease – INTREPID Study
Objective: To evaluate neuropsychological outcomes in subjects participating in the INTREPID randomized controlled trial (RCT). Background: Neuropsychological evaluation in the context of Deep Brain Stimulation…Development of an unsupervised analysis pipeline for human microelectrode recordings
Objective: Our aim is to develop computational tools that can assist clinical decision in Deep Brain Stimulation (DBS) for Parkinson's disease (PD) using intraoperative microelectrode…Effects of Directional Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s disease
Objective: To assess if a horizontal current steering in the subthalamic nucleus (STN) by directional deep brain stimulation (dDBS) offers clinical advantages compared to conventional…MRI based Volumetric analysis of the sub-thalamic and red nuclei in Advanced Parkinson’s disease- an institutional study
Objective: •To evaluate volume of Sub thalamic and Red nuclei on 3T MRI and its 3D reconstruction and its possible correlation with the disease progression in…Interleaved deep brain stimulation for dyskinesia management in Parkinson’s disease
Objective: To evaluate the clinical effects of using interleaving stimulation to simultaneously treat Parkinson’s disease (PD) symptoms and dyskinesia by the generation of two symptom-specific…Changing for a rechargeable neurostimulator in Parkinson’s disease patients: safety and feasibility
Objective: This study aimed to determine the feasibility and safety of the replacement of non-rechargeable implanted pulse generator (IPG) by rechargeable ones. Background: DBS of…Diagnosis and management strategies used in series of Parkinson’s disease patients who experienced subthalamic nucleus deep brain stimulation induced mood elevation
Objective: To describe the diagnosis and management of deep brain stimulation-induced elevated mood states. Background: Deep brain stimulation (DBS) is an FDA-approved surgical treatment option…Is Microelectrode Recording mandatory for Deep Brain Stimulation in Parkinson’s disease?
Objective: To find whether microelectrode recording (MER) is mandatory for deep brain stimulation (DBS) in Parkinson’s disease. Background: DBS is traditionally done using MER guidance.…
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