DIRECT DBS: A Prospective, Multicenter Clinical Study with Double-Blinding for a Directional Deep Brain Stimulation Lead – Intra-visit Impedance Changes
Objective: To evaluate impedance changes throughout the course of a programming visit as a part of a larger directional lead exploration study. Background: Historically, DBS…Blinded acute assessment of electrode contact efficacy compared with contact location for Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease
Objective: This study aimed to assess the clinical efficacy of each contact and the correlation between the clinical best contacts and radiologically defined optimal contacts.…Effect of bilateral subthalamic nucleus deep brain stimulation on quality of life in advanced Parkinson’s disease patients
Objective: To evaluate the effect of bilateral subthalamic nucleus deep brain stimulation( STN DBS) on motor control, quality of life (QOL) and cognition in a cohort of…Subcortical involvement in phonological input processing: an electrophysiological registration study
Objective: The current study applied direct electrophysiological registration of the local field potential activity in the thalamus, subthalamic nucleus (STN) and the pedunculopontine nucleus (PPN)…Degree, onset and longevity of benefit achieved with Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) as assessed by the UPDRS.
Objective: To show the degree, onset and longevity of benefit achieved with STN DBS at our center. Background: At our center, we administer the UPDRS-III…The Volatility of Local Field Potential Oscillations in Dystonia and Parkinson’s disease
Objective: To assess the volatility of low frequency (4-12Hz) and beta-band (13-30Hz) oscillations in local field potentials (LFPs) in dystonia and compare this to LFPs…Information transfer between subthalamic area and forearm muscles during tonic muscle activity in Parkinson’s patients
Objective: We compare information transfer between forearm muscles and two subthalamic regions, namely the subthalamic nucleus (STN) and the zona incerta (ZI), during an isometric…UPDRS benefit from dual frequency DBS fields sculpted by intentionally overlapped interleaving
Objective: We show that UPDRS-III scores after interleaving compared to those prior to interleaving reflect a gain in benefit by lowered scores. Background: Previously, we…Outcomes of a Prospective, Multicenter International Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: To investigate the effectiveness and safety-related real-world outcomes of a multiple-source, constant current Deep Brain Stimulation (DBS) System in the treatment of levodopa-responsive Parkinson’s…Efficacy and tolerability of low-frequency deep brain stimulation during daytime only in Parkinson’s disease: a pilot study
Objective: To compare the efficacy and tolerability of low-frequency stimulation (LFS) during daytime only to LFS applied 24 hours a day, in PD patients bilaterally…
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