MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Tauopathies"

  • MDS Virtual Congress 2021

    Plasma microRNA expression profiling in patients with progressive supranuclear palsy. A five-microRNA panel in plasma was identified as a potential biomarker for progressive supranuclear palsy

    R. Yadav, P. Ramaswamy, P. Pal, R. Christopher (Bengaluru, India)

    Objective: Our objective was to identify differentially expressed, circulating miRNAs in PSP which could serve as diagnostic biomarker for this disease. Background: Progressive supranuclear palsy…
  • MDS Virtual Congress 2021

    Lateralized Tau Pathology in a Case of Lewy Body Dementia with Corticobasal Syndrome

    D. Coughlin, H. Coslett, C. Mcmillan, J. Phillips, E. Lee, J. Trojanowski, M. Grossman, D. Irwin (San Diego, USA)

    Objective: To measure bilateral in vivo and postmortem tau pathology in a well-characterized patient presenting with corticobasal syndrome (CBS) due to underlying neocortical stage Lewy…
  • MDS Virtual Congress 2021

    MAPT mutation frontotemporal dementia with parkinsonism: when previous results can skew the diagnosis

    R. Franco, TC. Aguiar, A. Morganho, P. Lobo, R. Dias, S. Aguiar (Funchal, Portugal)

    Objective: Case report presentation. Background: In frontotemporal dementia with parkinsonism (FTDP), several mutations in MAPT gene have been identified, and numerous family cases were reported,…
  • MDS Virtual Congress 2020

    Cognitive Differences Between Men and Women with Progressive Supranuclear Palsy

    E. Bayram, J. Jankovic, S. Reich, C. Marras, Y. Bordelon, D. Shprecher, R. Dubinsky, I. Litvan (La Jolla, CA, USA)

    Objective: (1) To evaluate the cognitive differences between men and women with progressive supranuclear palsy (PSP) and (2) to investigate whether sex has an effect…
  • MDS Virtual Congress 2020

    The severity and distribution of tau pathology distinguish corticobasal degeneration and progressive supranuclear palsy

    S. Koga, N. Ghayal, S. Roemer, D. Dickson (Jacksonville, FL, USA)

    Objective: To elucidate whether the severity and distribution of tau pathology reflect the clinical presentations in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Background:…
  • MDS Virtual Congress 2020

    Can we stage tau pathology in PSP?

    G. Kovacs, M. Lukic, D. Irwin, T. Arzberger, G. Respondek, E. Lee, D. Coughlin, A. Giese, M. Grossman, C. Kurz, C. McMillan, E. Gelpi, Y. Compta, J. van Swieten, C. Troakes, S. Al-Sarraj, J. Robinson, S. Roeber, S. Xie, V. Lee, J. Trojanowski, G. Höglinger (Phildelphia, PA, USA)

    Objective: To evaluate distribution pattern of tau pathology in different PSP clinical subtypes and develop a staging system. Background: Progressive supranuclear palsy (PSP) is a…
  • MDS Virtual Congress 2020

    18kDa Translocator Protein PET in 4-Repeat Tauopathies – A Cross-Sectional Single Center Study

    C. Palleis, J. Sauerbeck, L. Beyer, S. Harris, J. Schmitt, A. Finze, A. Nitschmann, G. Biechele, K. Boetzel, A. Danek, B. Rauchmann, M. Unterrainer, N. Albert, R. Rupprecht, P. Bartenstein, R. Perneczky, C. Haass, J. Levin, G. Hoeglinger, M. Brendel (Munich, Germany)

    Objective: The aim of this single center study was to analyse the potential of 18F-GE-180 TSPO PET as a biomarker in 4R-tauopathies. Background: The pathological…
  • MDS Virtual Congress 2020

    Long and short survival in Parkinson syndrome: pathology and genetics are key prognostic factors

    A. Rajput, C. Robinson, M. Farrer, E. Gustavsson, A. Rajput (Saskatoon, SK, Canada)

    Objective: To study the clinical, pathological and genetic profile of Parkinson syndrome (PS) cases that have > 20 years survival (long survival, or LS) compared…
  • MDS Virtual Congress 2020

    No frank biochemical evidence of proteinopathy in the cerebellar cortex of patients with essential tremor

    A. Rajput, A. Rajput, C. Tremblay, F. Calon, K. Melançon, E. Aubry-Lafontaine, E. Brochu, S. Paris-Robidas (Quebec, QC, Canada)

    Objective: This study was designed to determine the presence of common types of proteinopathies in the cerebellar cortex of patients who died with essential tremor…
  • MDS Virtual Congress 2020

    TAU pathology contributes to specific patterns of structural brain damage and neuropsychological heterogeneity in Huntington’s disease

    S. Martinez-Horta, J. Perez-Perez, R. Perez-Gonzalez, A. Horta-Barba, F. Sampedro, E. Rivas-Asensio, T. Xucla, M. Guasch, A. Campolongo, C. Izquierdo-Barrionuevo, J. Pagonabarraga, J. Kulisevsky (Barcelona, Spain)

    Objective: Explore the associations between CSF levels of neurofilament light chain (Nfl), total TAU (tTAU) and phosphorylated TAU (pTAU), structural brain damage and cognitive performance…
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