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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Tauopathies"

  • MDS Virtual Congress 2021

    Benign Progressive Supranuclear Palsy: mild pathology associated with parkinsonism

    B. Couto, I. Martinez-Balbuena, S. Lee, N. Visanji, A. Lang, G. Kovacs (Toronto, Canada)

    Objective: Objective: To describe the clinical presentation and neuropathology of cases where the degree of tau pathology is mild, and the neuronal loss is anatomically…
  • MDS Virtual Congress 2021

    An evaluation of the application of clinical research criteria for corticobasal degeneration in a large clinico-pathological series

    D. Lux, L. Wu, H. Ling, T. Warner, A. Lees, T. Revesz, Z. Jaunmuktane, J. Rohrer, H. Morris (London, United Kingdom)

    Objective: To evaluate diagnostic criteria for corticobasal degeneration (CBD) in relation to pathology and disease course. Background: The overlapping features of CBD and related conditions…
  • MDS Virtual Congress 2021

    Plasma microRNA expression profiling in patients with progressive supranuclear palsy. A five-microRNA panel in plasma was identified as a potential biomarker for progressive supranuclear palsy

    R. Yadav, P. Ramaswamy, P. Pal, R. Christopher (Bengaluru, India)

    Objective: Our objective was to identify differentially expressed, circulating miRNAs in PSP which could serve as diagnostic biomarker for this disease. Background: Progressive supranuclear palsy…
  • MDS Virtual Congress 2020

    Tau Neuropathology Associates with In Vivo Patterns of Neurodegeneration in Lewy Body Disorders

    N. Spotorno, D. Coughlin, L. Shaw, A. Chen-Plotkin, D. Weintraub, E. Lee, J. Trojanowski, C. McMillan, D. Irwin, M. Grossman (Philadelphia, PA, USA)

    Objective: Investigate the impact of Alzheimer’s disease (AD) co-pathology on an in vivo structural measure of neurodegeneration in Lewy Body disorders (LBD: Parkinson’s Disease and…
  • MDS Virtual Congress 2020

    Identification and characterization of anti-prionic compounds that disassemble Tau prions as a novel therapeutic approach for tauopathies

    D. Willbold, T. Altendorf, W. Hoyer, J. Mohrlüder (Jülich, Germany)

    Objective: Stabilization of monomeric Tau protein by transient and high-affinity binding ligands is a novel and highly innovative anti-prionic treatment strategy for tauopathies. Background: Tauopathies…
  • MDS Virtual Congress 2020

    Mixed pathologies in pancreatic beta-cells from subjects with neurodegenerative diseases and their interaction with prion protein

    R. Valenti, I. Martinez, I. Amat, I. Marcilla, G. Marti, L. Armengou, C. Caballero, M.R Luquin (Pamplona, Spain)

    Objective: We studied whether, as in the brain, pancreatic -cells of subjects with neurodegenerative diseases also present co-occurrence of other misfolded proteins. Furthermore, we also assessed…
  • MDS Virtual Congress 2020

    Clinical features and natural course of corticobasal degeneration and progressive supranuclear palsy presenting as corticobasal syndrome

    I. Aiba, M. Yoshida, T. Shimohata, Y. Hayashi, T. Sano, Y. Saito, S. Murayama, K. Hasegawa, Y. Iwasaki, M. Sakai, K. Wakabayashi, T. Komori, K. Nakashima (Nagoya, Japan)

    Objective: To compare clinical features and natural course of corticobasal degeneration (CBD) presenting as corticobasal syndrome (CBD-CBS) and progressive supranuclear palsy presenting as corticobasal syndrome…
  • MDS Virtual Congress 2020

    Cognitive Differences Between Men and Women with Progressive Supranuclear Palsy

    E. Bayram, J. Jankovic, S. Reich, C. Marras, Y. Bordelon, D. Shprecher, R. Dubinsky, I. Litvan (La Jolla, CA, USA)

    Objective: (1) To evaluate the cognitive differences between men and women with progressive supranuclear palsy (PSP) and (2) to investigate whether sex has an effect…
  • MDS Virtual Congress 2020

    The severity and distribution of tau pathology distinguish corticobasal degeneration and progressive supranuclear palsy

    S. Koga, N. Ghayal, S. Roemer, D. Dickson (Jacksonville, FL, USA)

    Objective: To elucidate whether the severity and distribution of tau pathology reflect the clinical presentations in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Background:…
  • MDS Virtual Congress 2020

    Can we stage tau pathology in PSP?

    G. Kovacs, M. Lukic, D. Irwin, T. Arzberger, G. Respondek, E. Lee, D. Coughlin, A. Giese, M. Grossman, C. Kurz, C. McMillan, E. Gelpi, Y. Compta, J. van Swieten, C. Troakes, S. Al-Sarraj, J. Robinson, S. Roeber, S. Xie, V. Lee, J. Trojanowski, G. Höglinger (Phildelphia, PA, USA)

    Objective: To evaluate distribution pattern of tau pathology in different PSP clinical subtypes and develop a staging system. Background: Progressive supranuclear palsy (PSP) is a…
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