Skin in the game: Small fiber neuropathy in Parkinson’s disease and atypical parkinsonisms.
Objective: The aim of our study was to compare somatic and autonomic small fiber density, through skin biopsy, in Parkinson's disease (PD) and atypical parkinsonisms…Deciphering Corticobasal Syndrome: are clinical features and FDG-PET imaging capable of predicting amiloyd status?
Objective: The present study aimed at establishing clinical and brain functional patterns at FDG-PET that could distinguish Corticobasal Syndrome(CBS) variants due to AD from Tau pathology based on Pittsburgh Compound…Complement C3a receptor antagonist attenuates tau hyperphosphorylation via glycogen synthase kinase 3β signaling pathways
Objective: To investigate the role and mechanism of C3a receptor in okadaic acid（OA） induced SH-SY5Y cells tau hyperphosphorylation model Background: Neurofibrillary tangles aggregated from hyperphosphorylated…Heavy metals implicated in a geographical cluster of progressive supranuclear palsy induce tau accumulation and apoptotic cell death in cultured neurons
Objective: To test the hypothesis that certain metals may cause cellular damage suggesting tauopathy. This is an early step in testing the hypothesis that environmental…Cortical and subcortical atrophy in typical and variant Parkinson-plus syndromes: PROSPECT-M-UK study
Objective: To investigate grey matter volume in typical and variant Parkinson-plus syndromes, to correlate these with disease severity, and to assess regional atrophy within disease…PASSPORT, An Ongoing Phase 2 Study in Patients with PSP– Baseline Characteristics
Objective: To describe baseline characteristics of the participants with progressive supranuclear palsy (PSP) enrolled in the ongoing PASSPORT (NCT03068468) phase 2 study. Background: PSP is…Open-label extension (OLE) of a multiple ascending dose (MAD) study of BIIB092 in participants with PSP: Safety analysis
Objective: To assess safety of BIIB092 in participants with progressive supranuclear palsy (PSP) in an OLE of a MAD study. Background: BIIB092 is a humanized…Neuropathology of a South Korean with Perry syndrome with DCTN1 T78C mutation
Objective: To analyze macroscopic and microscopic findings of the Korean patient with Perry syndrome (PS), who had been already established about clinical features with genetic…Prevalence and characteristics of patients with progressive supranuclear palsy (PSP) in US health insurance claims data
Objective: To estimate the prevalence of PSP in the United States (US) and present a profile of PSP patients. Background: Progressive supranuclear palsy (PSP) is…Burden of progressive supranuclear palsy: A systematic literature review
Objective: The objective of this research was to identify available data on burden of progressive supranuclear palsy (PSP), a 4-repeat tauopathy. Research questions focused on…
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