Loss of cortical inhibition in Parkinson’s disease
Objective: To evaluate motor cortex inhibition at different stages of Parkinson’s disease (PD). Background: In PD, striatal dopamine depletion produces profound alterations in the neural…Differentiating Parkinson’s disease dementia and mild cognitive impairment from idiopathic Parkinson’s disease using machine learning approach
Objective: This paper aims at creating a computer-based diagnosis tool which can predict the classification of MCI and dementia in patients of Parkinson's disease (PD)…Lack of depotentiation may not be a hallmark of Levodopa-induced dyskinesias
Objective: Paired associative stimumlation (PAS)-induced plasticity, a form of spike-time dependent plasticity (STDP), is deficient in PD. We tested whether (1) PAS-induced plasticity could be…Effect of regular practice of yoga versus aerobic exercise on motor and non motor signs and motor cortex plasticity in Parkinson’s disease
Objective: To test whether the regular practice of yoga (1) improves motor and non-motor symptoms and signs in Parkinson’s disease (PD) more than aerobic training…Maladaptive motor cortex plasticity off medication in Parkinson’s disease patients with levodopa-induced dyskinesias
Objective: To test the hypothesis that motor cortex plasticity is maladaptive in Parkinson's disease (PD) patients suffering from dyskinesias, as compared to non-dyskinetic patients. Background:…Sensorimotor inhibition relates to gait dysfunction in people with Parkinson’s disease
Objective: To determine how sensorimotor inhibition relates to objective measures of gait OFF and ON levodopa and how having Parkinson’s disease (PD) affects this relationship.…Abnormal Intracortical Facilitation in patients of Parkinson’s disease with REM Sleep Behavior Disorder
Objective: To evaluate the motor cortical excitability changes in PD patients with and without RBD. Background: There has been an increase in the understanding of…Defining biomarkers to discriminate between organic and functional dystonia
Objective: Establish methodologies, fast and easy to translate to clinics, that help discriminate between organic and functional dystonia. Background: Functional dystonias are challenging diagnoses that…Cerebellar transcranial magnetic stimulation with neuronavigation for postural instability in PSP
Objective: We created a TMS protocol for paired-pulse cerebellar-M1 stimulation and repetitive cerebellar stimulation to augment cerebellar-brain inhibition and reduce postural instability in progressive supranuclear…Neurophysiologic characterization of Re-emergent tremor (RET) in Parkinson’s disease
Objective: To investigate: 1) the contribution of primary motor cortex (M1) to the generation of re-emergent tremor (RET) and rest tremor by measuring the Cortico-muscular…
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