Safinamide in Parkinson’s disease
Objective: To evaluate clinical effects, safety and tolerability of safinamide add-on levodopa in Parkinson’s disease (PD) patients. Background: Safinamide is a recently approved adjunctive treatment…Feasibility and Efficacy of Brainstem Modulation Therapy for the Management of Parkinson’s Disease
Objective: To evaluate the feasibility and potential efficacy of a software-controlled, solid-state caloric vestibular stimulation (CVS)-mediated brainstem modulation device for the treatment of non-motor and…Efficacy of zonisamide on motor symptoms in dementia with Lewy bodies: A post-hoc analysis of a phase 3 study
Objective: To characterize the efficacy of zonisamide in improving motor symptoms, we performed a post-hoc analysis using data from a phase 3 study that evaluated…A Phase 2 Efficacy Study of CX-8998, a Potent and Selective T-Type Calcium (Cav3) Modulator in Parkinson’s disease Tremor (PDT) Patients: Design and Dose-Selection Rationale
Objective: The objective of this study is to access the efficacy of CX-8998 using the MDS-UPDRS Tremor Score (MDS-UPDRS-TS) and a digital biomarker platform, while…STN deep brain stimulation can directly suppress levodopa-induced dyskinesia in Parkinson’s disease
Objective: The study aims to evaluate the effect of bilateral STN-DBS on levodopa-induced peak-dose dyskinesia in patients with PD. Background: Dyskinesia is among the most…Advanced Parkinson’s disease Diagnosis and Treatment Trends in Israel – Sub-Analysis of the OBSERVE-PD Multi-Country, Cross-Sectional Study
Objective: The primary objective of this observational study was to evaluate the proportion of Parkinson’s disease (PD) patients identified as advanced PD (APD) patients according…Alleviation of freezing of gait in patients with Parkinson’s disease by high-frequency rTMS over SMA is associated with normalization of brain connectivity patterns
Objective: We explored the efficacy and neural mechanisms of repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area (SMA) on freezing of gait (FOG)…Single limb stance test performance – Difference between tremor dominant and akinetic rigid dominant parkinson’s disease – A pilot study
Objective: The objective of the study is to compare single-limb stance test performance between tremor dominant (TD) and akinetic rigid dominant (ARD) Parkinson's disease patients.…A case of early onset parkinsonism caused by PLA2G6 gene mutation
Objective: To report and follow up a case of early-onset parkinsonism (EOP) caused by mutation of PLA2G6 gene and to improve the understanding and treatment…PPMI driven sample size estimation for clinical trials in Parkinson’s disease
Objective: To utilize clinical, imaging and CSF data from the Parkinson’s Progression Markers Initiative (PPMI) to estimate the sample size for disease modification studies in…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.