Identifying therapeutic targets from spontaneous beneficial brain lesions
Objective: To determine whether rare cases in which spontaneously occurring brain lesions improved tremor can be used to identify a therapeutic target. Background: The search…Cortical thinning as a neuroimaging marker of cognitive decline in X-linked dystonia-parkinsonism
Objective: To investigate whether alterations of cortical thickness correspond to cognitive dysfunction in XDP patients. Background: X-linked dystonia-parkinsonism (XDP) is a severe, hereditary movement disorder…Exploring the neural correlates of gait asymmetry in idiopathic REM Sleep Behaviour Disorder
Objective: Given the typical asymmetric onset of motor symptoms in PD, the current study sought to investigate whether patients with iRBD show evidence of asymmetric…[11 C] DASB PET imaging in dopa-responsive dystonia patients: The role of serotonin in motor and non-motor symptoms
Objective: To assess the non-displaceable binding potential (BPND) of the serotonin transporter (SERT) in dopa-responsive dystonia (DRD) patients and to determine if an altered BPND…Toward optimized nonlinear deformation algorithms for subcortical DBS target regions in MRI
Objective: 1. To evaluate and optimize subcortical accuracy of commonly used nonlinear deformation algorithms. 2. To optimize accuracy of automated atlas-based segmentation of the two…The impact of thalamic lesions on visuomotor behavior: A behavioral and fMRI study
Objective: Analysis of thalamic lesion-induced deficits on oculomotor and reaching behaviour: a psychophysical and fMRI study Background: Lesion studies and cortical connectivity suggest that higher-order…Cognition related to striatal dopaminergic function in healthy subjects, in consideration to aging
Objective: The aim of the present study was to find the relationship between striatal dopamine transporter (DAT) and cognitive function in healthy subjects and these…Superior cerebellar peduncles atrophy of PSP on PADRE imaging; comparison with idiopathic PD
Objective: The purpose of our study was to determine whether atrophy of Superior cerebellar peduncles (SCP) on phase-weighted magnetic resonance imaging technique (PADRE) was useful…Comparison of Volumetric MRI measurements between Dementia with Lewy bodies and prodromal Lewy body disease
Objective: To compare the volumetric changes between patients at prodromal stage of Lewy body disese and individuals with dementia with Lewy Bodies. Background: Volumetric magnetic…Correlation between cerebral perfusion and striatal dopamine transporter activity by dual SPECT study in Parkinsonian syndromes
Objective: We aimed to investigate the correlations between brain perfusion and striatal dopamine transporter (DAT) activity in parkinsonian syndromes and to characterize the difference in…
