Social hindrances for diagnosing Huntington’s disease
Objective: The need to differentiate the malingering from real complains Careful history can give a strong clue for the diagnosis Criminals can have diseases also…Myoclonus in adult onset Huntington’s disease
Objective: We present a case report of adult onset Huntington's disease (HD) with myoclonus as the main clinical feature. Background: Myoclonus is seldom reported as…Evaluation of serum sestrin protein in Parkinson’s disease: a plausible diagnostic marker
Objective: In this study, we evaluated the concentrations of sesn1 and sesn2 in the serum of 50 PD patients and 60 elderly controls. Aging is…Parkinson ‘ s disease and Peripheral Nervous System : Wax and Waning Non-motor offs and Levodopa-use Topics
Objective: To relate the non-motor offs theory , sensory signs and levodopa use with neurophysiiology terms in PD Background: Peripheral Nervous System disease concept in…Synthesis and pharmacological evaluation of 16-aryldieno steroids as anti-parkinsonian agents in LPS induced Neuroinflammation Model of Rat
Objective: The present study is aimed at design and synthesis of new therapeutically useful steroidal neuroprotective derivatives as anti-parkinsonian agents. The new 16-aryldieno steroidal derivatives…Parkinsonism in the very old – A clinicopathological study
Objective: To identify, spectrum of Parkinson variants, clinical features and course of disease in age > 80 year onset cases. Background: Old age is the…Metabolomic biomarkers strongly differentiate PD from healthy controls (HCs) in BioFIND study* specimens
Objective: To determine if metabolomic analysis - untargeted profiling of small-molecule (<1.5 kDalton) biochemical constituents - can yield useful diagnostic biomarkers of PD using CSF…Skin nerve phosphorylated α-synuclein deposits in idiopathic REM sleep behavior disorder.
Objective: Here we tested if p-syn deposits can be detected with the same approach in patients affected with idiopathic RBD (iRBD), as an early histopathological…Longitudinal study of freezing of gait in patients with Parkinson’s disease
Objective: We conducted a prospective hospital based cohort study to investigate the incidence of Freezing of gait (FOG) and variables associated with onset of FOG…Axial signs in early-stage Parkinson’s disease : an influence of the genotype ?
Objective: To assess the association between the genotype and the axial signs. Background: Regarding the onset of axial signs in Parkinson’s Disease (PD), heterogeneity has…
