Neuroimaging Factors Differentially Associated with Pathology and Clinical Presentation
Objective: Examine utility of a factor analysis approach to neuroimaging data in Lewy body disease (LBD) and Alzheimer’s disease (AD). Background: Significant heterogeneity exists among patients…Botulinum Toxin and Deep Brain Stimulation in Dystonia
Objective: The primary outcome was the relationship between BoNT dosage and DBS surgery in each muscle. A secondary analysis of BoNT dosages through different muscle…Loneliness Relates to Gait Over Other Features of Parkinsonism
Objective: To assess the relationship between loneliness and facets of parkinsonism in community-based samples. Background: Loneliness increases the risk of mortality, dementia, depression, and motor…Comparison of Spontaneous Brain Activity in Distinguishing Parkinsonian Variant of Multiple System Atrophy from Parkinson’s Disease at Early Stage
Objective: The primary objective was to explore distinctions in the fractional amplitude of low-frequency fluctuation (fALFF) indicator among early-stage parkinsonian variant of multiple system atrophy…Longitudinal Structural and Functional Correlates of Progression in Isolated Rapid Eye Movement Sleep Behaviour Disorder
Objective: To identify progressive structural and functional imaging alterations in a longitudinal cohort of patients with isolated rapid eye movement sleep behavior disorder (iRBD). Background:…[18F]PR04.MZ PET CT as a clinical tool in the differential diagnosis of PD and other atypical parkinsonian syndromes in the first 5 years of symptoms
Objective: Investigate if the [18F]PR04.MZ PET CT is a useful tool in the differential diagnosis of PD and atypical parkinsonian syndromes (AP), mainly MSA and…Hemiparkinsonism Induction with 6-OHDA in Primates Does Not Induce SN Hyperechogenicity.
Objective: We aimed to investigate the changes in SN echogenicity in primate models of hemiparkinsonism induced by 6-OHDA. Background: Hyperechogenicity in the midbrain demonstrated by…A Double-blind, Randomized, Crossover Clinical Trial comparing VIM vs. PSA Deep Brain Stimulation for Disabling Essential Tremor
Objective: To compare the efficacy, safety, energy efficiency and quality of life (QoL) of bilateral PSA-DBS versus bilateral VIM-DBS in the treatment of essential tremor…Transforming Parkinson’s Care in Africa: Establishing a Global Virtual Support Group for Africans Impacted by Parkinson’s Disease
Objective: To establish a monthly Global Virtual Support Group for Africans impacted by Parkinson's disease as part of the Transforming Parkinson’s Care in Africa (TraPCAf)…Istradefylline therapy for dystonia in Parkinson’s disease
Objective: To clarify the basal ganglia network links between PD and Dystonia in PD (Dys-PD) co-occur, and to get the conceptually novel pharmacotherapy. Background: Dys-PD is one…
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