Association of high-density lipoprotein cholesterol and related inflammatory index with neurodegeneration in drug-naïve dementia with Lewy bodies
Objective: We aimed to clarify the association of serum cholesterol levels and related inflammatory index with the degeneration of nigrostriatal dopaminergic neurons and clinical symptoms…Clinical and Pathological Features of CSF1R-Related Disorder Associated with the c.2330G>A, p.R777Q Pathogenic Variant
Objective: To report the clinical and pathological features of CSF1R-RD associated with the c.2330G>A, p.R777Q variant, and to report a new family carrying this variant.…Natural history and epidemiological study of multiple system atrophy in Hokkaido: HoRC-MSA 2014-2025
Objective: To investigate epidemiological information of multiple system atrophy (MSA) patients in Hokkaido, Japan by using the registry data from the Hokkaido Rare-disease Consortium for…Changes in Inhibitory Control Differentiate Progressive Supranuclear Palsy from Early Parkinson’s Disease
Objective: To describe distinct type of errors and frequency of perseverative errors in executive, memory, language, and attentional tasks in PSP and PD. Background: Progressive…Juvenile parkinsonism masquerading as hereditary spastic paraplegia
Objective: To present a patient with juvenile parkinsonism initially presented with billateral foot dystonia and inreased deep tendon reflexes. Background: Patients with juvenile parkinsonism may…Expanding the Geographic Spectrum of Guam Complex: A Case Report from Colombia
Objective: To describe the case of a patient presenting with a progressive neurodegenerative syndrome characterized by the coexistence of dementia, parkinsonism, and motor neuron disease.…LRRK2 Mutation in a Patient with NMDA and GAD 65 Antibodies
Objective: To describe case of a patient who presented with a history of autoimmune encephalitis with NMDA receptor and GAD 65 antibodies positive in cerebrospinal…The Absence of Normal Pressure Hydrocephalus Imaging Features in US Veterans with Parkinsonism: A Retrospective Imaging Study
Objective: To understand if there is co-existence of parkinsonism and normal pressure hydrocephalus (NPH) in a US VA cohort. Background: NPH poses diagnostic challenges in…Temporal disease patterns prior to Progressive Supranuclear Palsy diagnosis
Objective: To identify Progressive Supranuclear Palsy (PSP) disease trajectories, defined as the pattern of diagnoses over time, prior to PSP diagnosis in electronic health records.…Comparison of Prodromal Features between Parkinson’s Disease and Dementia with Lewy Bodies over 15 Years
Objective: Compare the association of classic prodromal features with subsequent development of Parkinson’s Disease (PD) versus Dementia with Lewy Bodies (DLB). Background: DLB shares pathology…
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