Can a global measure of cognition be used to inform balance interventions in Parkinson’s disease?
Objective: To examine the relationship between domains of cognition, using the Montreal Cognitive Assessment (MoCA), and domains of balance, using the Mini Balance Evaluation Systems…Path To Prevention (P2P) Therapeutics Platform Trial in Biomarker Defined Prodromal Parkinson’s Disease: Study Design
Objective: To describe the study design and proposed timeline of the first interventional study in biomarker defined prodromal Parkinson’s Disease (PD). Background: P2P is a…Pharmacological Invivo and invitro potential of resveratrol in experimental rat models of Parkinson’s disease
Objective: Aim of study was to elucidate the pharmacological Invivo and invitro effects and mechanisms of action ofRT in experimental models of PD. Background: The…Pilot study of outpatient rehabilitation of patients with Huntington’s disease in Russia
Objective: The benefits of exercises and physical activity in Huntington's disease in terms of motor function, gait speed, and balance, as well as a range…User Experience (UX): Successful Remote Engagement Strategy for Individuals at Risk for Parkinson’s Disease in PPMI
Objective: Describe participant engagement practices for progressive User Experience (UX) in a remote risk screening study. Background: Digital instruments continue to gain footing in clinical…A phase 2 randomized, double-blind, placebo-controlled trial of Ambroxol as a disease-modifying treatment for Parkinson’s disease dementia.
Objective: To evaluate the safety and tolerability of repurposing Ambroxol as a disease modifying treatment for Parkinson’s Disease Dementia (PDD). Background: Carrying a mutation in…Levodopa-entacapone-carbidopa-infusion treatment in Parkinson’s disease: A six-month follow-up study
Objective: Objectives of this study were to evaluate changes in medication, adverse events and early discontinuations of levodopa-entacapone-carbidopa-intestinal-gel (LECIG) treatment in advanced Parkinson’s disease (PD).…refractory myoclonus after COVID-19 with resolution after corticosteroids; a case report with brain biopsy and serial neuroimaging.
Objective: To present an individual with multifocal myoclonus after COVID-19 infection with resolution of bilateral MRI hyperintensities following corticosteroids use. Background: Myoclonus after Covid-19 infection…Istradefylline effect on Parkinson’s Disease Tremor, Motor symptoms and non-Motor symptoms.
Objective: Istradefylline is FDA approved for use in patients with PD treated with carbidopa-levodopa to reduce off time. GUH Movement Disorder Group has observed that…Impulse Control Disorder and medication management in Patients with Early-Onset Parkinson’s Disease
Objective: To assess the usage frequency of dopamine agonists (DA), the prevalence of impulse control disorder (ICD) in patients with Early-onset Parkinson’s Disease (EOPD), and…
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