Cognitive Side Effects to Initial Levodopa Exposure as a “Red Flag”: A Retrospective Study
Objective: To assess if presence of cognitive side effects during an initial levodopa trial suggests the ultimate diagnosis of atypical Parkinson (APD) vs Parkinson disease…Utilization of Skin Punch Biopsy for the Diagnosis of Alpha-synucleinopathy in Clinical Practice
Objective: To understand the use of skin punch biopsies for diagnosis and management of α-synucleinopathy within a large medical system. Background: Skin punch biopsy has…AI for Personalized Medication Management in Parkinson’s Disease
Objective: To assess medication usage over time in Parkinson’s Disease utilizing AI in EHR data. Background: Parkinson's disease (PD) is a complex neurodegenerative disorder characterized…α-Synuclein Seed Amplification Assay Amplification Parameters and Progression in Parkinson’s Disease
Objective: To examine the relationship between the reaction parameters of the cerebrospinal fluid (CSF) αSyn seed amplification assay (αSyn-SAA) to the risk of developing motor…Path To Prevention (P2P) Therapeutics Platform Trial in Stage 2B Neuronal Alpha-Synuclein Disease: Study Update
Objective: To describe the study design and timeline of the first interventional study in Neuronal α-Synuclein Disease (NSD). Background: P2P is a platform, Phase 2…Manganese-induced Parkinsonism Vs Rotenone-induced Parkinsonism: Animal Life Matters!
Objective: To evaluate the Parkinsonism mimicking potential of MnCl2 in an experimental rat model.To compare the destructive effect of MnCl2 with rotenone by performing behavioral,…Clinical Profile of Motor Complications in Parkinson’s Disease Patients at A National Tertiary Hospital In Indonesia
Objective: To analyse factors associated with motor complications in Parkinson's disease at a national tertiary referral hospital in Indonesia. Background: As Parkinson's disease progresses, levodopa…Oral health in Parkinson’s disease patients from countries with different economies: preliminary results of the OralPark study.
Objective: To characterize oral health in Parkinson’s disease (PD) patients from countries with different economies. Background: Oral diseases are the most frequent conditions globally and…Changes in Postural Control of Patients with Normal Pressure Hydrocephalus After Lumbar Puncture
Objective: To evaluate the alterations in postural control among patients diagnosed with normal pressure hydrocephalus (NPH) following lumbar puncture Background: Posturography is an indispensable tool…Pallidotomy as a Therapeutic Option for Patients with Advanced Parkinson’s Disease: Case Study
Objective: The aim of this research is to assess unilateral pallidotomy as a surgical alternative for Parkinson's Disease (PD), emphasizing improvements in contralateral motor symptoms…
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