Apolipoprotein E e4 genotype affects early motor progression in Parkinson’s disease through an effect on cognition
Objective: To evaluate the relationship between APOE e4 genotype, cognition, and motor progression in early Parkinson’s disease (PD). Background: The Apolipoprotein E (APOE) e4 genotype…Evaluation of Cognitive Assessment Tools in Parkinson’s Disease
Objective: To evaluate a variety of cognitive assessment scales in a longitudinal Parkinson’s disease (PD) cohort. Background: Cognitive impairment is one of the most common and…Adverse Events of Opicapone Adjunctive Therapy in 60 Consecutive Patients
Objective: This study aimed to investigate the risk of adverse events (AEs) when opicapone (OPC) was added as adjunctive therapy to L-dopa administration. Background: Levodopa…A multicenter, matched case-control study of alpha-synuclein accumulation in the gastrointestinal tract of Parkinson’s disease
Objective: 1) To determine the possibility as a pathologic biomarker of alpha-synuclein (AS) accumulation in the gastrointestinal (GI) tract in patients with Parkinson’s disease (PD) and…Estrogen and progesterone influence membrane functions and glucose transporter expression in synaptosomes of different age groups of naturally menopausal rats
Objective: The objective of this study was to determine the effect of 17 β-estradiol (E2) and progesterone (P4) on the activities of Na+ K+ ATPase, monoamine…Effects of physical exercise interventions on cognitive function in Parkinson’s disease: an updated systematic review and meta-analysis of randomized controlled trials
Objective: To determine whether physical exercise interventions can improve cognitive function, including overall performance and specific domains, in patients with Parkinson’s disease (PD) and to…Sex-specific speech correlates of dysphagia in Parkinson’s disease
Objective: To identify speech characteristics that directly correlate with dysphagia in advanced Parkinson's disease (PD) patients, using both acoustic and perceptual analyses of speech, with…Rapid cognitive decline and new-onset psychosis after GPi DBS in a severe GBA mutation carrier: a case demonstrating the importance of genetic screening pre-DBS
Objective: To report the impact of globus pallidus internus (GPi) Deep Brain Stimulation (DBS) on cognition and neuropsychiatric symptoms in a severe glucocerebrosidase (GBA1) mutation…Theoretical Definition of DBS Electrode Misplacement
Objective: To propose a definition of Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) electrode misplacement (MP) based on ideal brain connectivity strength. Background: MP is defined…Effect of levodopa on the interpretation of social interactions in people living with Parkinson’s disease
Objective: Better understand the social interactions by assessing the effect of oral levodopa on the social cognition abilities in fluctuating PD patients without significant cognitive disorder.…
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