Abstracts Archive - Page 657 of 1554 - MDS Abstracts

MDS Virtual Congress 2020
Cardiac Autonomic Dysfunction in Patients with Multiple System Atrophy: A cross-sectional study
G. Ganagarajan, T.N Sathyaprabha, K. Udupa, M.R Raghurama, K. Kuravatti, B.S Prasad, R. Yadav, K. Kambhampati, P. John (Bangalore, India)
Objective: The study aimed to assess cardiac autonomic dysfunction in patients with multiple system atrophy (MSA). Background: MSA is a progressive neurodegenerative disorder with predominant…
MDS Virtual Congress 2020
Body Weight-Supported Treadmill Training Improves Walking Function in Multiple System Atrophy: A Case Report
R. Hand, C. Testa (Richmond, VA, USA)
Objective: Multiple system atrophy (MSA) is a rapidly progressive synucleinopathy involving autonomic dysfunction and impaired mobility. MSA has been further sub-classified into two phenotypes: parkinsonian…
MDS Virtual Congress 2020
Age and gender differences in cardiovascular autonomic failure in transgenic PLP-syn mouse model of multiple system atrophy
M. Kermorgant, D. Arvanitis, P.O Fernagut, W. Meissner, J.M Senard, C. Galès, A. Pavy-Le Traon (Toulouse, France)
Objective: The main objective of the present study was to determine age and gender differences in measures of CAF in PLP-syn mice, a transgenic mouse…
MDS Virtual Congress 2020
CHCHD2 mRNA levels in erythrocyte are reduced in patients with multiple system atrophy
G.l Liu, X.d Liu, T. Feng (Beijing, China)
Objective: To investigate CHCHD2 mRNA expression of erythrocyte in patients with multiple system atrophy (MSA). Background: Coiled-coil-helix-coiledcoil-helix domain containing 2 (CHCHD2) are reported to be associate with…
MDS Virtual Congress 2020
Brain 5-HT1 receptor binding in multiple system atrophy: A [18F]-MPPF PET study
M. Meyer, I. Sibon, F. Lamarre, J. Asselineau, A. Foubert-Samier, J. Mazère, A. Delamarre, O. Rascol, A. Pavy-Le Traon, F. Tison, P. Fernandez, W. Meissner (Bordeaux, France)
Objective: The primary objective was to compare brain 5-HT1a receptor binding between patients with multiple system atrophy (MSA) and healthy controls (HC). The secondary objectives…
MDS Virtual Congress 2020
Disease stage and UMSARS progression: Implications for clinical trials
M. Pérez, J.A Palma, L. Norcliffe-Kaufmann, P. Millar Vernetti, W. Singer, P. Low, M.T Pellecchia, H.J Kim, C. Shibao, A. Peltier, I. Biaggioni, D. Giraldo, M.J Martí, A. Fanciulli, C. Terroba-Chambi, M. Merello, D. Goldstein, R. Freeman, C. Gibbons, S. Vernino, F. Krismer, G. Wenning, H. Kaufmann (New York, NY, USA)
Objective: To study the rate of progression of multiple system atrophy (MSA) and assess for a potential ceiling effect of the Unified Multiple System Atrophy…
MDS Virtual Congress 2020
Electrochemical skin conductance as a marker of autonomic failure in patients with Multiple System Atrophy
S. Perez-Lloret, V. Fabry, F. Ory-Magne, C. Brefel-Courbon, A. Foubert-Samier, W. Meissner, O. Rascol, J. Senard, A. Pavy-Le Traon (Toulouse, France)
Objective: We investigated the interest of a quick and non-invasive assessment of sweating as a marker of autonomic failure (AF) in Multiple System Atrohpy (MSA).…
MDS Virtual Congress 2020
Clinical profile and cerebral metabolic characteristic of cognitive impairments in multiple system atrophy
C. Shen, F.T Liu, JJ. Ge, P. Wu, C.T Zuo, J. Wang (Shanghai, China)
Objective: This study aimed to characterize the cognitive profiles of multiple system atrophy (MSA) and explore the possible mechanisms involved using 18F-fluorodeoxyglucose (FDG) Positron Emission…
MDS Virtual Congress 2020
Quantitative evaluation of Multiple System Atorphy by triaxial accelerometers and 9-hole peg test
S. Shirai, C. Sato, M. Matsushima, I. Yabe, H. Sasaki (Sapporo, Japan)
Objective: We need a concise and responsive biomarker for multiple system atrophy (MSA). Background: In Japan, the majority of patients of MSA are of the…
MDS Virtual Congress 2020
GCI-induced neurodegeneration and synucleinopathy in non-human primates
M. Teil, S. Dovero, M.L Artocarena, M. Bourdenx, G. Porras, B. Mollenhauer, M.T Herrero, M. Vila, J. Obeso, B. Dehay, E. Bezard (Bordeaux, France)
Objective: This study aimed at determining the potential to induce MSA pathology in non-human primates. Background: Aggregation of alpha-synuclein has been implicated in several neurodegenerative…