Beta synchronization of the subthalamic nucleus during self-initiated and externally generated movement in parkinsonian patients in OFF and ON states
Objective: The aim of this study is to estimate the level of beta synchronization of the subthalamic nucleus (STN) evoked by internally and externally generated…Longitudinal changes of gait parameters in early Parkinson’s disease
Objective: To analyse changes in quantitative gait parameters in patients with very early, unilateral, PD over 12 months follow-up. Background: Parkinson’s disease (PD) is frequently characterized by progressive gait…High intensity exercise improves Sleep EEG Delta Power in Parkinson’s Disease
Objective: This novel study tests the hypothesis that 16 weeks of high-intensity exercise rehabilitation combining resistance training plus body-weight interval training, compared with a sleep…Early Adapter: Study Protocol for the Multi-Center Post-Market Study of Adaptive Deep Brain Stimulation (aDBS) in Japan
Objective: To assess the procedures for introducing two adaptive deep brain stimulation (aDBS) modes (single and dual threshold) in Parkinson’s disease patients (PD) in a…Influence of deep brain stimulation on premotor-motor interaction in patients with Parkinson’s disease
Objective: To investigate the interaction between subthalamic nucleus (STN), dorsal premotor (PMd), and primary motor cortex (M1) in patients with Parkinson’s disease (PD) in vivo by coupling…Distinct oscillatory fingerprints in dyskinesias mediated by D1 versus D2 receptors
Objective: To characterize the patterns of cortico-basal ganglia oscillations induced by D1 or D2 receptor agonists in a rat model of L-DOPA-induced dyskinesia. Background: In…Chronic sensing of the subthalamic nucleus in Parkinson’s disease patients: preliminary observations
Objective: Here we document the key advances and pitfalls of the PerceptTM PC (Medtronic), a commercially available device capable of recording brain local field potentials…Enhanced arm swing improves Parkinson gait associated with EEG power modulations resembling those in healthy gait.
Objective: To examine whether enhanced arm swing improves Parkinsonian gait and explore the role of the supplementary motor area (SMA) in such an improvement. Background:…Abnormalities of vestibular-evoked myogenic potentials are associated with REM sleep without atonia in early Parkinson’s disease and idiopathic REM sleep behavior disorder
Objective: To explore the brainstem lesion reflected by means of vestibular-evoked myogenic potentials(VEMPs) and its association with REM sleep without atonia(RSWA) and other clinical assessments…Progression of neuroinflammation in patients with isolated REM sleep behavior disorder. A 11C-PK11195 PET study
Objective: The aim of this study was to investigate in vivo the progression of neuroinflammation iRBD patients over a 3-year follow-up. Background: Isolated rapid-eye-movement behaviour…
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