Novel PET Tracers of alpha-synuclein for the diagnosis of Parkinson’s disease
Objective: The aim of our project is to develop small molecular weight compounds (Morphomers™) which bind selectively to alpha-synuclein (aSyn) aggregates, in order to generate…DTI in Parkinson’s disease: Asymmetric progression
Objective: To study the rate of change of brain region diffusion tensor imaging (DTI) parameters between the right and left sides in PD patients using…Critical path for Parkinson’s II: Global regulatory agencies support the use of dopamine transporter neuroimaging as an enrichment biomarker to enable clinical trials in early Parkinson’s disease
Objective: This presentation focuses on neuroimaging of the Dopamine Transporter as an enrichment biomarker in clinical trials of Parkinson's disease (PD). Background: The Critical Path…A longitudinal study of functional deterioration of primary olfactory cortex in early-stage Parkinson’s disease
Objective: To study the dynamic changes of the olfactory cortex function in the early-stage Parkinson's disease (PD) using functional magnetic resonance imaging (fMRI). Background: Olfactory…The evaluation of metabolic differences by using 18F-FDG-PET/CT in demented and non demented Idiophatic Parkinson’s disease patients
Objective: The objective of this study was to identify metabolic group differences between Idiopatic Parkinson's disease patients with dementia (PDD) and without dementia (PD), by…Accuracy of clinical diagnosis of dementia with Lewy bodies: A systematic review and meta-analysis
Objective: To perform a systematic review of the studies on diagnostic accuracy in dementia with Lewy bodies (DLB) and to meta-analyse sensitivity, specificity and accuracy…Investigation of driving ability to drive safely in patients with Parkinson’s disease by interview
Objective: We investigated the vehicle driving situation, clinical signs and symptoms of PD patients to obtain the information for safe driving. Background: PD neurologists are…Visual hallucinations may serve as a possible predictor for Parkinson’s disease dementia
Objective: To observe whether visual hallucinations serve as a predictor of Parkinson's disease dementia. Background: Visual hallucinations (VH) is one of non-motor symptoms in Parkinson's…Quantifiable changes in cortical visual processing in patients with Parkinson’s disease but no cognitive impairment
Objective: To demonstrate quantifiable differences in cortical visual processing in patients with Parkinson's disease with no evidence of dementia, as compared to controls. Background: Visual…Effects of gender, age and hyposmia on cognitive functions in healthy elderly individuals at risk for Parkinson’s disease: Results from the TREND study
Objective: To evaluate the impact of gender, age and hyposmia on the cognitive performance in memory, language, executive, and visuo-spatial functions to set the stage…
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