Prevalence, Distribution and Management of Parkinson among Pakistani Population
Objective: To evaluate clinical spectrum and management of the parkinson disease(PD) among Pakistani population. Background: Parkinson, an idiopathic, slowly progressive neuro-degenerative syndrome characterized by bradykinesia,…A Phase 2A Study of Nilotinib in Patients with Advanced and Early Parkinson’s disease: Study Design
Objective: To assess the safety and tolerability of nilotinib (150-300 mg QD) in moderate/advanced and early/de novo Parkinson disease (PD) participants. Background: Studies in cell…Compensation strategies for gait impairments in Parkinson’s disease
Objective: To provide an overview of available compensation strategies for gait impairments in Parkinson’s disease (PD) using an expert-opinion based methodology. Background: Patients with PD…Real-World Outcomes Using a Novel Directional Lead from a Deep Brain Stimulation (DBS) Registry for Parkinson’s Disease
Objective: The objective of this report is to assess the initial real-world outcomes using a directional lead with a Deep Brain Stimulation (DBS) system capable…Peripheral nerve grafts implanted into the substantia nigra in patients with Parkinson’s disease during deep brain stimulation surgery: 2-year follow-up study of gait parameters
Objective: Measuring gait parameters in patients with Parkinson's disease (PD) who underwent autologous peripheral nerve grafts implantation (surgical deployment of the Schwann cells obtained from…The BeyoND study: Design and baseline characteristics of a study evaluating the long-term safety of ND0612 for motor fluctuations in Parkinson’s disease
Objective: Describe the design and baseline characteristics of a long-term (1 year) study of 2 ND0612 dose regimens, with emphasis on systemic and local safety…Development of a biomarker for Parkinson’s disease by measuring alpha-synuclein oligomers in cerebrospinal fluid with ultrasonication-induced amyloid fibril formation
Objective: To establish a new technique quantifying misfolded alpha-synuclein (αSyn) oligomers in the CSF and to investigate their clinical - pathological significances in Parkinson’s disease…Exercise to improve upper limb function in people with Parkinson’s disease: A systematic review
Objective: To review the effectiveness and describe the exercise parameters of interventions targeting upper limb (UL) function in people with PD. Background: Reduced fine hand…The effects of treadmill training augmented by virtual reality on postural control and freezing of gait in Parkinson’s disease
Objective: To investigate whether treadmill training with virtual reality is beneficial both for Parkinson’s disease patients with and without freezing of gait (FOG) to address…Efficacy of CVT-301 (levodopa inhalation powder) for treatment of OFF periods in Parkinson’s disease
Objective: Post-hoc analysis of subjects with Parkinson’s disease (PD) achieving > 30% reduction in UPDRS motor score (UPDRSIII) from pre- to post-dose over the first…
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