Short and long-term Impact of Covid-19 Pandemic on motor and non-motor symptoms in Leucine-rich repeat kinase2 (LRRK2) associated Parkinson’s disease
Objective: To determine short and long-term impact of COVID-19 on motor(MS) and non-motor(NMS) symptoms among Tunisian PD patients according to Leucine-rich repeat kinase2 (LRRK2)-carrying status.…Connectivity matrices for differentiating voluntary stopping states and involuntary freezing states in Parkinson’s disease
Objective: The present study aims to demonstrate a possible application of the analysis of functional brain connectivity from brain connectivity matrices. Specifically, we aim to: - Differentiate…Diagnostic accuracy of dopamine SPECT in degenerative parkinsonism compared to neuropathological diagnosis.
Objective: To evaluate diagnostic accuracy of dopamine SPECT against neuropathological diagnosis in a large cohort of patients with parkinsonism. Background: Diagnosis of parkinsonian syndromes remains…Studying Care Patterns and Support Preferences Among People Living with Parkinson’s Disease
Objective: To understand health care utilization among Medicare beneficiaries living with Parkinson’s Disease (PD) and how care patterns differ across demographic groups. Background: Optimal care…LRRK2 Inhibition by BIIB122: Trial designs for two efficacy and safety studies in Parkinson’s disease patients with and without LRRK2 mutations (Lighthouse and Luma)
Objective: Describe Luma and Lighthouse, two studies that investigate efficacy and safety of BIIB122, a LRRK2 inhibitor. Background: Increased LRRK2 kinase activity has been linked…Feasibility of using ENROLL-HD for health services research: Evaluation of delays in Huntington’s Disease (HD) Diagnosis
Objective: To describe social and structural determinants of health of HD patients and to evaluate the feasibility of using this dataset for health services research.…GLUT1 Deficiency Syndrome with Novel mutation responsive to GPi DBS
Objective: To describe a case of a patient with a progressive primary isolated generalized dystonia of childhood onset associated to a novel SLC2A1 mutation with…The study of clonidine growth hormone study amongst definite MSA, PD, PSP, and PAF patients to assess its feasibility as a future non-invasive biomarker
Objective: To analyze the sensitivity and specificity of the clonidine growth hormone (CGH) to distinguish probable multiple system atrophy (MSA) from pure autonomic failure (PAF),…The Edmond J. Safra Fellowship in Movement Disorders: A Global Network of Parkinson’s Experts
Objective: To train more movement disorder clinician-researchers around the world to meet growing care and research needs in Parkinson’s and related disorders. Background: Care from…Evaluation of Genetic influence of APOE on Clinical and motor functions among Idiopathic Parkinson’s Disease Patients; A comparative study
Objective: We studied the effect of APOE ε4 carriers and non-carriers on clinical and motor functions in patients with IPD Background: The significance of APOE…
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