Decline in functionality according to WHODAS 2.0 associated with disease progression in people with Parkinson’s disease
Objective: To investigate the decline in functionality according to WHODAS-2.0 from early to intermediate stages of PD. Background: Parkinson's disease (PD) is an incurable and…Lessons from the COVID-19 Lockdown: A Novel Mentorship Program for Young Neurosurgeons, Neurologists and Medical Students
Objective: To propose novel virtual mentorship program as a teaching tool to improve career skills among young Neurosurgeon and Ophthalmologists. Background: COVID‐19 pandemic has caused…Evaluation of Neurotransmitter and Co-transmitter Expression in the Aging Human Locus Coeruleus: Relevance to Neurodegenerative Disorders.
Objective: To analyze the age-associated changes in the neurotransmitter/co-transmitter expression and morphometric profiles of human locus coeruleus (LC) neurons using autopsied human tissues. Background: LC…The Pro-LBD Study Investigating Early Detection, Prognosis, and Biomarkers of Prodromal Lewy Body Diseases
Objective: The Pro-LBD cohort study is a prospective, long-term, clinic-biological cohort study of participants who are stratified by their risk of developing a Lewy body…Hyposmia is Associated with Positive CSF α-Synuclein Seeding in Normal Pressure Hydrocephalus
Objective: To detect α-synuclein (αSyn) pathology and associated clinical characteristics in patients with idiopathic normal pressure hydrocephalus (iNPH) through cerebrospinal fluid (CSF) αSyn seed amplification…Adult Onset Spastic Paraplegia in TUBB4A Leukodystrophy
Objective: Introduction: Leukodystrophies are primarily known as childhood diseases, but recent advances in genetic testing and brain imaging have led to an increase in reports…Prospective Study of Gait and Multimodal MRI Biomarkers for Multiple System Atrophy
Objective: We aimed to develop new multimodal biomarkers allowing objective monitoring of early MSA progression to improve outcome definition for future neuroprotective trials. Background: MSA…Characteristics of Language Abnormalities in Multiple System Atrophy and Parkinson’s Disease
Objective: We characterized complex language profile and explore diagnostic potential of automated language analysis of natural spontaneous speech in differentiation between multiple system atrophy (MSA)…Longitudinal progress and clinical relevance of 18F-Florzolutau PET in patients with PSP: a one-year follow-up study
Objective: Here we aimed to explore the progress of 18F-Florzolotau PET and its clinical relevance in patients with PSP during one-year follow-up. Background: The 18F-Florzolotau…Spectrum of Sleep abnormalities in Patients with Progressive supranuclear palsy
Objective: We studied the clinical characteristics of patients with Progressive Supranuclear Palsy (PSP) with particular reference to sleep disorders and their associated features. Background: PSP…
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