Long term evaluation of gluten-free diet in Parkinson´s disease patients
Objective: The primary aim of the project was to evaluate the effect of long-term administered gluten-free diet (GFD) on motor symptoms of Parkinson's disease (PD).…Istradefylline therapy for dystonia in Parkinson’s disease
Objective: To clarify the basal ganglia network links between PD and Dystonia in PD (Dys-PD) co-occur, and to get the conceptually novel pharmacotherapy. Background: Dys-PD is one…Preclinical Studies: Investigating Serum-Based Exosomal miRNAs in Prodromal Drug-Induced Parkinson’s Disease
Objective: This work aims to elucidate the identification of homologs of miRNAs in a pronormal stage of Parkinson`s disease. Background: Parkinson's disease (PD) is defined…Differences in Molecular and Ultrastructural profiles of astroglia and microglia in substantia nigra of two different mice strains in normal aging and experimental Parkinsonism
Objective: To examine whether the variable sensitivity of dopaminergic neurons of the substantia nigra pars compacta -SNpc- in C57BL/6J and CD-1 mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/ MPTP…Exercise Mitigates DNA Methylation Changes at cg17274742 Associated with the Circadian Gene Variant PER2 rs2304672: A Biobank Analysis
Objective: This research aims to dissect the influence of physical activity and circadian rhythms on neuroinflammation and neurodegenerative disease progression, focusing on Parkinson's Disease (PD).…The role of extracellular vesicles in the progression of Parkinson’s disease
Objective: The objective of this study is to investigate the role of extracellular vesicles (EVs) in the progression of Parkinson’s disease Background: Parkinson’s disease (PD)…A Visual Interpretation Algorithm for Assessing 18F-Florzolotau PET Scans in Progressive Supranuclear Palsy
Objective: This study aimed to develop a visual reading algorithm dedicated to the evaluation of 18F-Florzolotau positron emission tomography (PET) scans in PSP. Background: The…The value of DaT SPECT in rare movement disorders: acquired diseases
Objective: To explore the expanding indications of dopamine transporter imaging (DaT SPECT) beyond the already known indication in Parkinson Diseases (PD) Background: DaT SPECT is…Accuracy of AI-driven automated diagnostic software analyzing Susceptibility Map-Weighted Imaging to Differentiate Neurodegenerative from Non-neurodegenerative Parkinsonism
Objective: To determine the accuracy of AI-driven automated diagnostic software analyzing susceptibility map-weighted imaging (SMWI) to distinguish neurodegenerative from non-neurodegenerative parkinsonism in patients who had…Whole-brain functional network signature reflecting conversion of isolated REM sleep behavior disorder
Objective: The aim was to investigate the brain functional network alteration /pattern as a measure to identify the conversion from idiopathic rapid eye movement sleep…
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