A new tool to measure the impact of deep brain stimulation on Parkinson’s disease patients: Development and validation of the deep brain stimulation impairment scale (DBS-IS)
Objective: To develop a questionnaire that measures impairments related to deep brain stimulation (DBS). Background: DBS has considerable influence on motor and non-motor symptoms in…Motor and non-motor symptoms in Parkinson’s disease: Correlation and impact on quality of life and activities of daily living
Objective: To evaluate the prevalence, interrelation and impact on health related quality of life (HRQL) and Activities of daily Living (ADL) of motor (MS) and…Apathy and striatal dopamine defects in non-demented patients with Parkinson’s disease
Objective: We performed this study to investigate whether dopamine depletion in the ventral striatum contributes to apathy in PD. Background: Apathy is a common, disabling…Impact of subclinical apathy prior to deep brain stimulation on the quality of life of patients with Parkinson’s disease
Objective: To evaluate the influence of pretreatment subclinical apathy on patient QOL following subthalamic nucleus DBS (STN-DBS) in PD patients 12 months after surgery. Background:…Relationship between the MDS-UPDRS and quality of life in Parkinson’s disease: A large international multicenter study of 3206 patients (the QUALPD study)
Objective: To evaluate the relationship between the International Parkinson and Movement Disorder Society – Unified Parkinson's disease Rating Scale (MDS-UPDRS) and Quality of Life (QoL)…Relationships of cognitive functions and psychiatric symptoms with motor phenotypes in patients with untreated early-stage Parkinson’s disease
Objective: It has been shown that the clinical types of Parkinson's disease (PD) based on motor symptoms include motor phenotypes of postural instability and gait…Apathy phenotype in Parkinson’s disease: Motor and non-motor features
Objective: To evaluate whether apathy is associated with specific motor and non-motor features in patients with Parkinson's disease. Background: In a previous clinical cohort study…Depression and apathy in restless legs syndrome
Objective: We examined the prevalence of mood disorders (depression, apathy) and its' characteristics. Moreover, to investigate pathophysiology of the mood disorders in the patient in…Neuroanatomical correlates of apathy in non-demented and non-depressed Parkinson’s disease
Objective: We aimed to explore the neuroanatomical correlates of isolated apathy in PD by means of voxel-based morphometry (VBM) analysis and its correlates with other…Anhedonia and its correlation with clinical aspects in Parkinson’s disease
Objective: The aim of this study is to evaluate the characteristics of anhedonia and its correlation with clinical aspects of PD in a relatively large…
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