Validation of the PD Home Diary for Assessment of Motor Fluctuations in Advanced Parkinson’s Disease
Objective: To determine the validity of the Parkinson’s disease (PD) home diary for quantification of motor states in patients with advanced PD and motor fluctuations.…TREMOR AND BRADYKINESIA ARE TWO UNRELATED SIDE EFFECTS INDUCED BY VALPROATE INTAKE
Objective: To better characterize clinical and neurophysiological features of valproate-induced tremor in patients with epilepsy and the effect of valproate on the execution of voluntary…Anatomical Substrates for Motor Subcomponents of Bradykinesia in Parkinson’s Disease after Subthalamic Nucleus Deep Brain Simulation
Objective: To evaluate distinct anatomical substrates modulating motor subcomponents of bradykinesia following Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS) in Parkinson’s Disease (PD). Background: PD…Exploratory analysis of the effect of delayed-start prasinezumab on motor sign progression measured with the Roche PD Mobile Application v2: PASADENA Phase II Parts 1 and 2
Objective: To determine whether the positive effects of prasinezumab on motor progression measured by Roche PD Mobile Application (PASADENA study Part 1; 0-52 weeks; NCT03100149)…EFFECTS OF OPICAPONE IN PARKINSON DISEASE AS ASSESSED BY KINEMATIC TECHNIQUES
Objective: We aimed to objectively investigate the effects of Opicapone on bradykinesia in Parkinson's Disease (PD) by kinematic analysis. Background: By increasing L-dopa bioavailability, catechol-O-methyl…Remote keyboard tapping: potential signatures of early motor dysfunction in isolated REM sleep behaviour disorder
Objective: To compare keyboard tapping performance in people with iRBD with controls. Background: The Distal Finger Tapping (DFT)1 test and BRadykineisa Akinesia Incoordination test (BRAIN)2…Ocular ping pong movement to disentangle apathy from Bradykinesia in Parkinson’s disease
Objective: To disentangle bradykinesia from apathy through analysis of ocular movements. Background: While Parkinson's disease (PD) is mainly characterized by motor symptoms such as bradykinesia,…Clinical Manifestations Of Mn-Induced Parkinsonism In The Workers Of Manganese Ferroalloy Ore
Objective: We aimed to assess the clinical characteristics and symptoms of chronic manganese intoxication in workers involved in grinding the manganese ore in the Zestafoni…Pallidal beta activity correlates with stimulation-induced bradykinesia in dystonia patients
Objective: Identify a neurophysiological correlate of stimulation-induced bradykinesia in dystonia Background: Bradykinesia is a known side-effect of pallidal deep brain stimulation (DBS) in dystonia patients…Determinants of symptom severity in Parkinson’s disease: the International Vacation Survey
Objective: As insight in the drivers of varying symptom severity might help manage symptoms, this study investigates the association between symptom severity and contextual factors…
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