Safety, Target Engagement and Effects of Bosutinib in Dementia with Lewy Bodies
Objective: To investigate the safety, biomarkers effects and determine the lowest effective dose of Bosutinibin Dementia with Lewy Bodies (DLB) Background: The effects of bosutinib,…Predicting cognitive decline using neuropsychiatric symptoms in prodromal Lewy body disease.
Objective: To investigate the influence of neuropsychiatric symptoms (NPS) on early cognitive decline in patients with Lewy body disease (LBD). Background: NPS in LBD, including…Plasma p-tau181 is increased in Lewy body dementia and relates to cognitive performance
Objective: To compare plasma p-tau181 concentration in Parkinson’s disease (PD), Lewy body dementia (LBD) and healthy controls and to examine the relationship between ptau-181 concentration…Lewy body disease clinical subgroups present similar disease progression rates
Objective: To characterize LBD clinical subgroups and identify possible differences in disease progression. Background: Patients with Lewy body disease (LBD) present a wide variety of…Survival and progression in GBA-associated dementia with Lewy bodies
Objective: To assess the impact of GBA mutations and APOE polymorphisms on progression and survival in a cohort of Ashkenazi Jewish (AJ) patients with DLB.…Evaluation of Actigraphy-Based Circadian Rhythm and Motor Function Measures for Monitoring Treatment of Lewy Body Dementia in PRESENCE Study
Objective: To evaluate if wrist actigraphy data can derive clinically meaningful information reflecting circadian rhythm and motor functions from patients with Lewy body dementia (LBD)…Neuropsychological correlates of Cognitive fluctuations in dementia with Lewy bodies
Objective: To examine which neuropsychological characteristics are associated with cognitive fluctuations (CF) in patients with dementia with Lewy bodies (DLB). Background: СF are core diagnostic…Distinct amyloid-dependent patterns of nigral dopamine depletion in Lewy body diseases
Objective: To investigate the effect of amyloid on striatal 18F-FP-CIT uptake patterns in Lewy body disease (LBD), including Parkinson’s disease (PD) and dementia with Lewy…Sleep stability, arousals and cycle structure in alfa-synucleinopathies: a comparative study between isolated REM sleep behaviour disorder (iRBD), Parkinson’s Disease (PD) and Dementia with Lewy Bodies (DLB)
Objective: To compare sleep stability, arousals and sleep cycle structure between two sets of diagnosis: iRBD vs PD vs DLB; patients with RBD (RBD+) vs…Differentiation of Mild Cognitive Impairment (MCI) progression to Alzheimer Disease (AD) vs Dementia with Lewy Bodies (DLB): Is this possible neuropsychologically?
Objective: Aim of the present review study was to describe and compare the neurocognitive features of MCI which could predict its progression to DLB vs…
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