MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Dopamine"

  • 2023 International Congress

    Levodopa Carbidopa Intestinal Gel for Parkinson’s Disease over 11 years: A Single Center “Real-World” Experience

    C. Vekhande, M. Hamed, G. Tremain, J. Mah, A. Shetty, A. Lazarescu, O. Suchowersky (Edmonton, Canada)

    Objective: To review long-term real-world experience and clinical outcomes in PD patients with LCIG therapy over 11 years in a multidisciplinary University clinic setting. Background:…
  • 2023 International Congress

    Ventral tegmental deep brain stimulation does not influence risk-taking behaviour in a standard gambling task

    S. Hirschbichler, S. Lagrata, M. Matharu, S. Manohar (St. Pölten, Austria)

    Objective:  We here used a standard gambling task that involved risky decision-making. This permitted us to measure the effects of ventral tegmental area (VTA) deep…
  • 2023 International Congress

    Parkin Coregulates Glutathione Metabolism in Adult Brain to Contribute to Redox Homeostasis

    D. El Kodsi, J. Tokarew, R. Sengupta, A. Chatterji, M. Takanashi, N. Hattori, J. Tomlinson (Ottawa, Canada)

    Objective: We sought to determine whether the expression of PRKN, a young-onset Parkinson disease-linked gene, confers redox homeostasis in vivo. Background: The mechanisms by which…
  • 2023 International Congress

    Dopamine depletion of striatal subregions and motor dysfunction in prodromal and clinical Parkinson’s disease

    M. Banwinkler, M. Hoenig, V. Dzialas, T. van Eimeren (Cologne, Germany)

    Objective: This aim of this study was to investigate how dopamine depletion of different striatal subregions contributes to motor symptoms in patients with prodromal and…
  • 2023 International Congress

    Diagnostic challenges in a case of SLC6A3-related Dopamine Transporter Deficiency Syndrome

    L. Jafri, J. Martindale (Winston Salem, USA)

    Objective: We report a case presenting with symptoms of classical Dopamine Transporter Deficiency Syndrome (DTDS) with negative results on initial whole-exome sequencing (WES), but eventually…
  • 2022 International Congress

    Impact of the dopamine system on long-term, incident cognitive impairment in Parkinson disease

    D. Weintraub, M. Picillo, H. Cho, C. Caspell-Garcia, C. Coffey, K. Marek, K. Poston, T. Simuni, J. Seibyl, A. Siderowf, A. Singleton, C. Tanner (Philadelphia, USA)

    Objective: To determine the impact of the dopamine system (dopamine transporter [DAT] availability, dopamine-related SNPs, and dopaminergic medication use) on long-term cognitive performance in early…
  • 2022 International Congress

    Changes in the level of glial neurotrophic factor in Parkinson’s disease depending on the form

    B. Muminov, R. Matmurodov, E. Abduqodirov (Tashkent, Uzbekistan)

    Objective: To study the level of glial neurotrophic disease in blood plasma in patients with Parkinson's disease (PD) depending on the form Background: Neurotrophic factors…
  • 2022 International Congress

    The study of genetic factors in motor levodopa-induced complications development in Russian patients with Parkinson’s disease

    G. Akhmadeeva, I. Khidiyatova, I. Gilyazova, S. Umutbaev, A. Baitimerov, O. Kachemaeva, R. Galimova, R. Magzhanov (Ufa, Russian Federation)

    Objective: This study is aimed to explore the relationship between the single nucleotide polymorphisms (SNPs) in dopamine metabolism genes and development of motor side effects…
  • 2022 International Congress

    Presynaptic dopamine compartmentalization defects initiate auxilin-mediated parkinsonism

    D J. Vidyadhara, M. Somayaji, N. Wade, H. Zhao, S. Narayanan, J. Gupta, T. Lam, D. Sames, L. Greene, D. Sulzer, S. Chandra (New Haven, USA)

    Objective: To evaluate the pathogenic mechanisms for auxilin-mediated Parkinson’s disease (PD). Background: Auxilin participates in uncoating of clathrin-coated vesicles (CCVs), thereby facilitating synaptic vesicle (SV)…
  • 2022 International Congress

    Impact of dopamine replacement therapies on MDS-UPDRS II

    F. Nassan, J. Shirvan, M. Yang, T. Dam, J. Wang, N. Maserejian, W. Flanders (Brookline, USA)

    Objective: To estimate the longitudinal effect of different dopamine therapies on the Movement Disorder Society-Sponsored Unified Parkinson's Disease Rating Scale Part II (MDS-UPDRS II) among…
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