Beyond Neurodegeneration: Anti-Recoverin Autoantibodies in Immune-Mediated Parkinsonism
Objective: To report a rare case of autoimmune Parkinsonism associated with anti-recoverin antibodies, highlighting atypical presentation , diagnostic challenges and immunotherapy response. Background: Parkinsonism is…L1CAM and TMEM119 enriched Exosomal markers in Parkinson’s Disease and Progressive Supranuclear Palsy: A Prospective Study
Objective: This study explored longitudinal changes in cellular inflammatory, autophagic mediators in L1CAM and TMEM119-enriched exosomal samples of patients with Parkinson’s disease (PD) and Progressive…Characterising Peripheral Innate Immune Cell Infiltration into the Brain in Parkinson’s Disease
Objective: To characterise the infiltration of peripheral innate immune cells (NK cells, monocytes and neutrophils) into the brain in Parkinson’s disease (PD) and to investigate…Peripheral unspecific inflammatory parameters – not always useful in differential diagnosis of parkinsonian syndromes.
Objective: To determine utility of systemic inflammation response index (SIRI) and systemic immune-inflammation index (SII) in differential diagnosis of Parkinson’s disease (PD), progressive supranuclear palsy-Richardson’s…Neutrophil Extracellular Traps Reveal Novel Inflammatory Signatures in Parkinson’s Disease and Multiple System Atrophy
Objective: This cross-sectional study investigates neutrophil extracellular trap (NET) activation in Parkinson’s disease (PD) and multiple system atrophy (MSA) by quantifying plasma levels of NET-associated…Inflammatory profile in LRRK2-associated prodromal and clinical PD:a cross-sectional study
Objective: To investigate the peripheral inflammatory cytokine levels and their associations with clinical severity, dopaminergic presynaptic degeneration in asymptomatic carriers and PD patients with LRRK2 mutation.To investigate…Neuroinflammatory response is determined by HLA genotype in progressive supranuclear palsy
Objective: Our aim was to examine whether the HLA haplotypes influence the neuroinflammatory response in a cohort of neuropathologically diagnosed PSP cases. Background: Progressive supranuclear…Plasma Protein Profiles Reveal Distinct Molecular Signatures in Parkinson’s Disease and Multiple System Atrophy
Objective: We aimed to identify distinct plasma proteins in patients with Parkinson’s disease (PD) and multiple system atrophy (MSA) and evaluate their associations with disease…Effects of conventional and adaptive deep brain stimulation on systemic oxy-Inflammation in Parkinson’s Disease
Objective: This study investigates the impact of conventional (cDBS) and adaptive deep brain stimulation (aDBS) on systemic oxidative stress (OxS) and inflammation in Parkinson’s Disease…Spectrum of Movement Disorders Associated With Autoimmune Thyroid Disease
Objective: To describe the spectrum of movement disorders in patients with positive anti-thyroid antibodies (ATA+). Background: Autoimmune thyroid diseases (AITD), including Hashimoto’s thyroiditis (HT) and…
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