Maladaptive motor cortex plasticity off medication in Parkinson’s disease patients with levodopa-induced dyskinesias
Objective: To test the hypothesis that motor cortex plasticity is maladaptive in Parkinson's disease (PD) patients suffering from dyskinesias, as compared to non-dyskinetic patients. Background:…A Patient with Gait Disturbance Caused by Parkinson’s Disease: A Case Report
Objective: It is well known that mental simulation of movement in the brain can facilitate motor rehabilitation. Our hypothesis is: can a direct, sequential stimulation…Left-right motor cortex asymmetry in the pathophysiology of essential tremor
Objective: To investigate left-right motor cortex asymmetry in the pathophysiology of essential tremor (ET). Background: ET is typically bilateral but usually manifests with mild asymmetry…The dopamine receptor antagonist haloperidol enhances beta and gamma oscillations and bursts in the motor cortex
Objective: We aimed to investigate the changes in oscillatory activity in the motor cortex (MCtx) and the sensorimotor cortex (SMCtx) of rats after acute injection…Parkinsonism alters directed connectivity in the cortico-subthalamo-pallidal circuit
Objective: To characterize how parkinsonism alters directed connectivity across the motor cortex (M1), subthalamic nucleus (STN), and internal segment of the globus pallidus (GPi). Background:…Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms
Objective: Using opto-activation of cortical interneurons, we aimed at mimicking the cortical effects of deep brain stimulation of the subthalamic nucleus (STN-DBS) to reproduce its…Ponto-cortical aberrations:Neural correlations for Hypomimia in PD
Objective: We team neuron, focused on analyzing progressive degeneration of neural structural connectivity of the tract from Brodmann area 4, part precentral gyrus to facial motor…Case Report: Co-occurrence of Motor Neuron Disease and Parkinsonism
Objective: Explore possible links between degenerative parkinsonism and motor neuron disease Background: A 50 year-old man developed with the cardinal features of parkinsonism. History was…Effects of the Neuromodulation of Sensorimotor Rhythms on the Event-Related Desynchronization Phenomenon in Parkinson’s Disease
Objective: The main goal of this work relies on the study of the desynchronization of the sensorimotor rhythms in Parkinson’s disease (PD). Electrophysiological cortical activity…Motor intracortical excitability before speech onset in adults who stutter
Objective: A core feature of persistent developmental stuttering is the paroxysmal, transient, involuntary loss of speech motor control. However, the neurophysiology of stuttering remains largely…
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