Maladaptive motor cortex plasticity off medication in Parkinson’s disease patients with levodopa-induced dyskinesias
Objective: To test the hypothesis that motor cortex plasticity is maladaptive in Parkinson's disease (PD) patients suffering from dyskinesias, as compared to non-dyskinetic patients. Background:…A Patient with Gait Disturbance Caused by Parkinson’s Disease: A Case Report
Objective: It is well known that mental simulation of movement in the brain can facilitate motor rehabilitation. Our hypothesis is: can a direct, sequential stimulation…Left-right motor cortex asymmetry in the pathophysiology of essential tremor
Objective: To investigate left-right motor cortex asymmetry in the pathophysiology of essential tremor (ET). Background: ET is typically bilateral but usually manifests with mild asymmetry…Impaired intracortical inhibition predicts response to medication in Parkinson’s disease patients
Objective: To check whether measures of motor cortex excitability and plasticity are associated with clinical response to dopaminergic treatment in Parkinson’s disease (PD) patients. Background:…Impaired LTP-like plasticity in Parkinson’s Disease can be restored by γ-transcranial alternating current stimulation
Objective: To test whether the co-stimulation γ-transcranial alternating current stimulation (γ-tACS)-intermittent theta burst stimulation (iTBS) is effective in improving the impaired long-term potentiation (LTP)-like plasticity…Cortical gamma oscillations as biomarkers for levodopa-induced dyskinesia
Objective: The aim of our study was to characterize cortical neuronal network activity in levodopa-induced dyskinesia in order to better understand the underlying pathophysiology and…To respond or not to respond to paired associative stimulation: proof of intervention by cerebello-cortical circuit
Objective: To test whether the non-responder or responder status of primary motor cortex (M1) to an LTP- inducing paired associative stimulation (PAS) protocol in healthy…The dopamine receptor antagonist haloperidol enhances beta and gamma oscillations and bursts in the motor cortex
Objective: We aimed to investigate the changes in oscillatory activity in the motor cortex (MCtx) and the sensorimotor cortex (SMCtx) of rats after acute injection…Parkinsonism alters directed connectivity in the cortico-subthalamo-pallidal circuit
Objective: To characterize how parkinsonism alters directed connectivity across the motor cortex (M1), subthalamic nucleus (STN), and internal segment of the globus pallidus (GPi). Background:…Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms
Objective: Using opto-activation of cortical interneurons, we aimed at mimicking the cortical effects of deep brain stimulation of the subthalamic nucleus (STN-DBS) to reproduce its…
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