BASELINE OLFACTION TESTING IN PARKINSON’S DISEASE PATIENTS IS CORRELATED WITH LONG-TERM DOPAMINERGIC DENERVATION IN STRIATAL SUB-REGIONS: LONGITUDINAL DATA FROM THE PPMI STUDY.
Objective: The aim of the current study was to determine whether there are longitudinal differences in dopaminergic denervation of striatal sub-regions [signal reduction in 123I-FP-CIT…Relationship Between Hyposmia and Olfactory Network Connectivity in Patients With Parkinson’s Disease
Objective: To examine resting-state functional Magnetic Resonance Imaging in a group of Parkinson’s Disease patients, used to characterize changes in functional connectivity of the olfactory…Predictive value of UPSIT subsets in prodromal Parkinson disease
Objective: To assess the predictive value of previously published subsets of the University of Pennsylvania Smell Identification Test (UPSIT) odors for conversion to Parkinson disease…Serial olfactory testing for the diagnosis of prodromal Parkinson disease in the Parkinson Associated Risk Syndrome (PARS) study
Objective: To assess whether repeat olfactory testing in initially hyposmic subjects improves prediction of conversion to Parkinson disease (PD). Background: Hyposmia is a common prodromal…Smell dysfunction correlates with severity of motor deficits in H&Y stage-I early onset Parkinson’s disease
Objective: The objective of this study is to test the hypotheses that: 1) olfactory dysfunction in early stage Parkinson’s disease (PD) is correlated with severity…Improving estimation of Parkinson’s disease risk – enhancing the PREDICT-PD algorithm
Objective: To develop and test an enhanced algorithm for the prediction of Parkinson’s disease (PD) risk. Background: The PREDICT-PD algorithm estimates risk of PD using…Hyposmia as a biomarker in patients with Parkinson’s disease and atypical Parkinsonism
Objective: To investigate neural correlates associated with olfactory dysfunction using fMRI and EEG in Parkinsonism. Background: Patients with Parkinsonism experience non-motor symptoms during the onset…The role of dopamine mis-metabolism in preclinical Parkinson’s disease olfactory deficits
Objective: To gain an understanding of the underlying pathological mechanisms of Parkinson’s disease (PD)-related hyposmia using post-mortem human olfactory bulbs and an in vivo model…Difference in olfactory impairment between tremor dominant and akinetic rigid dominant Parkinson’s disease patients
Objective: To investigate difference in olfactory impairment between tremor dominant (TD) and akinetic rigid dominant (ARD) Parkinson’s disease patients. Background: PD can be classified in…Diagnostic value of olfactory dysfunction in Parkinson’s disease
Objective: To assess the olfactory performance in patients with PD using “Sniffin’ Sticks”. Background: Olfactory dysfunction is an important early premotor biomarker for PD, and…
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