When and how to stop subthalamic deep brain stimulation in late-stage Parkinson’s disease
Objective: We sought to investigate the percentage of “poor stimulation responders” among late-stage Parkinson's disease (LSPD) patients for elaborating an algorithm to decide whether and…Correlation of Lead Location with Clinical Outcomes in a Double-Blinded Randomized Controlled Trial Evaluating Subthalamic Deep Brain Stimulation in Parkinson’s Disease (INTREPID)
Objective: To assess the relationship between lead location in the subthalamic nucleus (STN) and deep brain stimulation (DBS) outcomes as reported in the INTREPID clinical…Deep learning approach for Parkinson’s disease classification from facial expressions: A pilot feasibility study
Objective: To apply deep learning and traditional machine learning approaches to images of different facial expressions from patients and controls to aid in the prediction…Sustained Improvement in Freezing of Gait (FOG) and Treatment Satisfaction at 12 months After Initiation of Carbidopa/Levodopa Enteral Suspension (CLES) in Advanced Parkinson’s Disease (APD) Patients in USA: Interim Results from the PROviDE Study
Objective: To evaluate the long-term effectiveness of CLES on FOG and treatment satisfaction in APD patients. Background: FOG, prevalent in about 60% of APD patients,…Art du Deplacement (ADD)/Parkour therapy for people with Parkinson’s disease (PDP)
Objective: The purpose of this study was to transfer ADD training methods into safe training paradigms for PDP, and psychologically framed coping strategies for mood…The Clinical Features of Parkinson’s Disease with 20 Years or More Survival
Objective: To evaluate the clinical demographic data in Parkinson’s disease (PD) survivors with 20 years duration and beyond (PD-20) and investigate the impact of age…Analysis of Levodopa Content in Commercial Formulations of Mucuna pruriens Seeds Used in Integrative Treatment of Parkinson’s Disease
Objective: Objective: Formulations of Mucuna pruriens (MP) seed products are readily available through the internet and health food stores, and are used by some Parkinson's…Oligomeric Alpha-synuclein in Erythrocyte Membrane in Early Parkinson’s Disease
Objective: To determine whether α-synuclein concentrations in the cell membrane and cytoplasm of erythrocytes are altered in PD patients and to evaluate their potential role…The French NS-PARK/FCRIN network: a 5-year balance sheet
Objective: To describe the achievements of the French NS-PARK/FCRIN network (http://www.parkinson.network/) after 5 years of activity. Background: The French Clinical Research Infrastructure network FCRIN is…The Frequency, Causes and Risk Factors of Discontinuation of Dopamine Agonists in Parkinson’s Disease Patients
Objective: To determine the incidence, causes and risk factors of dopamine agonists (pramipexole and ropinirole) discontinuation in Parkinson’s disease patients. Background: Ropinirole and pramipexole are…
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