Exploring anti-hypertensives as possible disease modifying agents in Parkinson’s disease using artificial intelligence and epidemiology
Objective: To apply machine learning and epidemiology to identify existing drugs that may have a disease modifying effect in Parkinson’s disease (PD). Background: Drug repurposing…Psychosis in Prodromal Parkinson’s disease
Objective: To investigate a possible association between psychosis and prodromal Parkinson’s disease (PD) in a population-based cohort, the Hellenic Longitudinal Investigation of Aging and Diet…Parkinsonism and other motor features in familial frontotemporal dementia with mutations in the MAPT, GRN, or C9orf72 gene (LEFFTDS cohort)
Objective: We compared motor features in patients with familial frontotemporal dementia (f-FTD) and MAPT, GRN or C9orf72 gene mutations. Special emphasis was placed on the evaluation…The role of X-chromosome inactivation in the penetrance of X-linked dystonia-parkinsonism in women
Objective: To investigate whether the combination of the X-linked dystonia-parkinsonism (XDP) haplotype and skewed X-chromosome inactivation (XCI) underlies the penetrance of XDP in women. Background:…Digenic inheritance of WARS2 and CHRNA6 mutations in infantile parkinsonism
Objective: To provide evidence of digenic inheritance in infantile parkinsonism. Background: Oligogenic inheritance has been demonstrated in PD[1],where patients with a primary genetic cause can…Entity of excessive daytime sleepiness in Parkinson’s disease
Objective: To examine frequency and reasons of excessive daytime sleepiness (EDS) in patients with Parkinson’s disease (PD). Background: Neurodegeneration and dopaminergic medications are known to…Complex disease burden in Parkinson’s and Advance Care Planning
Objective: To evaluate if Advanced Care Planning is completed in patients with complex stage of Parkinson’s Disease (PD). Background: NICE (National Institute of Health and…Is the activation ratio of transversus abdominis associated with mobility and core endurance in patients with Idiopathic Parkinson’s Disease?: A Preliminary study
Objective: This study aims to investigate the relationship between the transversus abdominis (TrA) muscle thickness changes using the activation ratio during abdominal drawing-in maneuver (ADIM)…Does cognitive-motor training improve the balance in Parkinson’s disease? Randomized clinical trial
Objective: To verify the effectiveness of adding cognitive training to motor physiotherapy compared to motor physiotherapy in balance, motor symptoms and activities of daily living…Digital biomarker sensor feature data reflect quality of life judgements (PDQ39) in recently diagnosed Parkinson’s disease patients
Objective: To evaluate the extent to which data derived from smartphone-based testing and passive monitoring are related to what recently diagnosed Parkinson’s disease (PD) patients…
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