Expanding the phenotypic spectrum of movement disorders in 22q11.2 deletion syndrome
Objective: To formally characterize the evolving spectrum of movement disorders associated with chromosome 22q11.2 deletion syndrome Background: Emerging evidence suggests that a wide range of…Rare Variant Association Analysis in Kazakhstani Parkinson’s Disease Population: Preliminary Results from GP2 CAT-PD Study
Objective: To identify rare genetic variants in genes, previously associated with Parkinson’s disease (PD) within a population consisting of individuals with PD and unaffected controls…Effects of Sample Collection Methods on Skin Sebum Volatilome Composition in Parkinson’s Disease Patients – a Methodological Pilot Study
Objective: To assess replicability of skin sebum volatile organic compound (VOC) composition 1) within the same subjects; 2) in frozen vs fresh samples, and 3)…Catalan MSA Registry (CMSAR): Applying new Clinical Criteria and Biomarkers for Increasing Diagnostic Accuracy, is New Better?
Objective: To reassess the CMSAR and determine if new criteria and new biomarkers can enhance diagnostic accuracy. Background: The CMSAR, conducted between 2015 and 2019,…Accuracy of Clinical features for Substantia Nigra Hypopigmentation and Cortical Lewy Body Presence in the Oldest-Old: The 90+ Study
Objective: To improve clinical diagnostic accuracy of Lewy Body Dementia (LBD), we assessed if frontal release signs are a useful screening tool for cortical Lewy…Mixed Brain Pathology in Neurodegenerative Parkinsonism and Dementia
Objective: To assess the presence of mixed neurodegenerative pathology and its proportion in the prospective cohort of patients treated for any phenotype of neurodegenerative parkinsonism,…Cognitive Side Effects to Initial Levodopa Exposure as a “Red Flag”: A Retrospective Study
Objective: To assess if presence of cognitive side effects during an initial levodopa trial suggests the ultimate diagnosis of atypical Parkinson (APD) vs Parkinson disease…Brainstem Monoaminergic Degeneration, Cognition, and Autonomic Symptom Progression in Early Parkinson’s Disease
Objective: In this study, we aimed to investigate the association between brainstem monoaminergic nuclear degeneration, particularly the serotonergic raphe and noradrenergic locus coeruleus, and cognitive…Can Simple Home Based Exercises Reduce the Fear of Falling in Parkinson Disorders?
Objective: To examine the potential benefit of a simple home-based gait and balance training on fear of fall in patients with Parkinson’s (PwP). Background: PwP…Preclinical Studies: Investigating Serum-Based Exosomal miRNAs in Prodromal Drug-Induced Parkinson’s Disease
Objective: This work aims to elucidate the identification of homologs of miRNAs in a pronormal stage of Parkinson`s disease. Background: Parkinson's disease (PD) is defined…
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