Anti-Parkinsonian effects of Globimetula cupulata leaf extract and its underlying mechanisms in 6-hydroxydopamine-lesioned rat model
Objective: To evaluate the neuroprotective effects of Globimetula cupulata in a rat model of Parkinson Disease (PD) induced by 6-hydroxydopamine (6-OHDA) injection in the striatum,…Co-Occurrence of DAT Scan, Amyloid PET Scan, and Alzheimer’s Genetic Screening Abnormalities in Patient with Early-Onset Neurocognitive Decline: A Case Report
Objective: The presented case report aims to show the possible overlap between causes of neurocognitive decline and the importance of considering comorbidities when discussing anti-amyloid monoclonal…Clinical Characteristics of Parkinsons Disease and their Role in Differential Diagnosis
Objective: To study and systematize the clinical characteristics of Parkinson's disease (PD) and their role in differential diagnosis with other parkinsonian syndromes. Background: Parkinson’s disease…Efficacy and Safety of Fecal Microbiota Transplantation in the Management of Parkinson’s Disease: A Systematic Review
Objective: 1. Assess the efficacy of FMT in PD by evaluating its impact on motor and non-motor symptoms.2. Determine the safety profile of FMT in…From Subclinical Symptoms to Post-Surgical Challenges: A Pediatric Case of Craniopharyngioma
Objective: To provide a case of subclinical symptoms including motor tics in a child found to have a large craniopharyngioma with post surgical parkinsonism. Background:…Novel Genetic Variant Associated with Parkinsonism
Objective: Case presentation of a novel genetic variant associated with parkinsonism. Background: Parkinsonism is a clinical syndrome characterized by a combination of bradykinesia, rigidity, tremor…Juvenile parkinsonism masquerading as hereditary spastic paraplegia
Objective: To present a patient with juvenile parkinsonism initially presented with billateral foot dystonia and inreased deep tendon reflexes. Background: Patients with juvenile parkinsonism may…Impact of manganese exposure on neurobehavioral disorders in rats: Insights into oxidative stress pathways and Parkinsonian syndrome pathophysiology
Objective: This study investigates the correlation between oxidative stress in various neural structures induced by manganese (Mn) and the onset of anxious and depressive behaviours…Quantitative evaluation of speech characteristics in Assessment of Motor Speech for Dysarthria (AMSD) using acoustic analysis
Objective: This study aims to extract acoustic features from speech data obtained from patients undergoing the Assessment of Motor Speech for Dysarthria (AMSD), a clinical…Promising Remote Markers of Motor Progression in Isolated REM Sleep Behaviour Disorder
Objective: To define the motor progression of motor prodromes using two remote keyboard tapping tests (BRAIN and DFT tests) and two remote standardised clinical rating…
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