Functional Hearing Impairment Common In Parkinson’s Disease: Insights From A Pilot Study
Objective: The primary objective of this pilot study was to investigate hearing and its relationship to the neuropsychiatric profile, cognition and quality of life in…Possible correlations between symptoms suggesting gastroparesis and dyskinesias in advanced Parkinson’s disease
Objective: The objective was to describe the spectrum of gastrointestinal complaints in a large cohort of patients with advanced Parkinson’s Disease (APD), who were repeatedly…Pulmonary function in Parkinson’s disease
Objective: To establish if pulmonary function is impaired in Parkinson’s disease (PD) and define any pattern of impairment. Background: Parkinson’s disease (PD) is associated with…WATCH-PD: Wearable Assessments in the Clinic and Home in Parkinson’s Disease: Study Design and Update
Objective: To determine whether digital measures can provide a progression profile in early Parkinson’s disease (PD) that is more sensitive and/or less variable than current…A Long-Term Safety, Tolerability, and Efficacy Study of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Interim Results
Objective: Evaluate the long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL-130277; APL) for on-demand treatment of “OFF” episodes in patients with Parkinson’s…Baseline results of a virtual longitudinal, observational study of Parkinson’s disease: The AT-HOME PD cohort
Objective: To describe the baseline characteristics of Parkinson’s disease (PD) clinical trial participants enrolled in a remote, long-term observational follow-up study. Background: Participation in clinical…Daily Time-Course of Efficacy of Continuous Subcutaneous Infusion of Foslevodopa/foscarbidopa in Advanced Parkinson’s Disease Patients from a Phase 1b Study
Objective: Characterize and compare the time-course of Parkinson’s disease (PD) symptoms following 24h/day continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa and oral levodopa/carbidopa (LD/CD). Background: As…Patients’ Perceptions of Herbal Medicine for Parkinson’s disease: Thai Perspectives on Cannabis and Mucuna Pruriens
Objective: To determine patients’ perceptions and knowledge of herbal medicine, including medical cannabis (MC) and Mucuna pruriens (MP), for the treatment of Parkinson’s disease (PD) Background: The use…The Effect of Rasagiline on Motor and Non-Motor Symptoms in Parkinson’s Disease
Objective: In this study, we aimed to evaluate the effect of rasagiline treatment on motor and non-motor symptoms in patients with Parkinson’s disease (PD). Background:…Physiologically-based pharmacokinetic modeling of nilotinib to determine serum, cerebrospinal fluid, and brain exposures
Objective: To construct a physiologically-based pharmacokinetic (PBPK) model for predicting nilotinib pharmacokinetics (PK) in plasma and cerebrospinal fluid (CSF); and, to compare model-predicted serum and…
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