Combined approach in the diagnostic of Parkinson’s disease
Objective: Our aim was to develop and scientifically substantiate set of criteria for early(preclinical) diagnosis of neurodegenerative disorders with the assessment of a number of…A novel motor-learning based dysphagia treatment approach in Parkinson’s disease
Objective: This pilot study tested the effectiveness of a novel motor learning and exercise principle-based dysphagia treatment approach in PD. Background: Dysphagia occurs in 90% percent…Pain in Monogenic Parkinson’s disease: A systematic review
Objective: We investigated the hypothesis that genotypes may influence pain phenotype in Parkinson's disease (PD) patients. The presence of pain, its subtypes, severity, and time in relationship…Association between severity of freezing of gait and turning characteristics in Parkinson’s disease
Objective: To investigate the turning characteristics of people with Parkinson’s disease (PD) with freezing of gait (FoG) according to the turning direction. Background: For people…The induction of mitochondrial damage by alpha synuclein In Parkinson’s disease.
Objective: Alpha synuclein aggregation have been indicted in the process of neuronal cell loss in Parkinson's disease; however, there have been several hypothesis to explain…Efficacy and safety of adjunctive oral therapy in Parkinson’s disease with motor complications: a systematic review and network meta-analysis
Objective: To review the evidence and compare the efficacy and safety of catechol-O-methyltransferase inhibitors (COMT-Is), dopamine agonists (DAs) and monoamine-oxidase B inhibitors (MAOB-Is) as adjunctive…Microstructural abnormalities of the dentato-rubro thalamo-cortical tract in tremor dominant PD and ET plus syndrome: A DTI, NODDI and free water-based analysis
Objective: To evaluate microstructural integrity of the dentato-rubro thalamo-cortical tract (DRTT) in tremor dominant Parkinson’s disease (TDPD) and ET plus (ETP) syndrome using a multimodal…Disease progression of data-driven subtypes of Parkinson Disease (PD): 5-year longitudinal study from The Early Parkinson’s disease Longitudinal Singapore (PALS) cohort
Objective: To evaluate the non-motor symptom(NMS), motor and cognition progression among the Parkinson Disease (PD) clusters derived from data-driven approach. Background: Data-driven PD subtypes were…Disruption of Locus Coeruleus-Related Functional Networks in Parkinson’s Disease
Objective: We used resting-state functional MRI (rs-fMRI) to investigate the alterations of functional connectivity (FC) of LC-related resting-state networks (RSNs) and the associations between RSNs…Serum Zinc Deficiency could be associated with dementia conversion in Parkinson’s disease
Objective: To investigate the role of depletion or excess of various heavy metals on clinical characteristics of Parkinson's disease (PD) developing PD dementia in drug-naïve…
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