MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Parkinson’s"

  • 2025 International Congress

    The regulatory variant c.–253C>T of the DNAJC13 gene as a causal factor for Parkinson’s disease in a patient with early-onset

    J. Hoenicka, A. Pascual, P. García-Ruíz, X. Castro-Martínez, R. Repossi, O. de Fabregues, L. Vela-Desojo, M. Mata, I. Torres, JC. Martinez-Castrillo, F. Palau, G. Fernandez (Mexico City, Mexico)

    Objective: This work aims to investigate the role of regulatory regions in Parkinson’s disease (PD) genes, which may help explain part of the missing heritability.…
  • 2025 International Congress

    Interrogating GCase Activity in Human Monocytes Isolated from Parkinson’s Disease Patients Carrying the Asian LRRK2 G2385R and R1628P Variants

    TS. Toh, JW. Hor, SY. Lim, LC. Lit, AN. Khairul Anuar, CY. Lew, YW. Tay, JL. Lim, A. Ahmad-Annuar, K. Zeneviciute, D. Alessi, E. Sammler, AH. Tan (Kuala Lumpur, Malaysia)

    Objective: To compare Glucocerebrosidase-1 (GCase) activity in human monocytes of manifesting LRRK2 G2385R, R1628P, and double-variant carriers vs. idiopathic Parkinson’s disease (iPD) and healthy controls…
  • 2025 International Congress

    Genetics of African Americans – Louisiana, Parkinson’s Disease – (GoAAL-PD)

    J. Staisch, S. Breaux, D. Thomas, C. Cevallos, C. Robinson, J. Hines, A. Bonano, L. Davis, J. Henry, N. Crovetto, E. Levenes (New Orleans, USA)

    Objective: Study a cohort of African American patients with PD to understand the genetic underpinnings, phenotypes, barriers to care, and engagement preferences unique to this…
  • 2025 International Congress

    Asymptomatic GBA1 Mutation Carriers Have Increased Cortical Cholinergic Activity

    M. Matarazzo, J. Mckenzie, S. Dhaliwal, Q. Miao, N. Vafai, R. Alcalay, V. Bruno, A. Lehman, J. Quinn, D. Raymond, D. Safarpour, J. Sarna, R. Saunders-Pullman, S. Sirrs, CP. Zabetian, V. Sossi, AJ. Stoessl (Vancouver, Canada)

    Objective: The objective of this study was to assess cholinergic activity changes in patients with Parkinson’s disease carrying GBA1 variants(GBA-PD) and in non-manifesting carriers(GBA-NMC) using…
  • 2025 International Congress

    Genetic analysis of the X chromosome and Parkinson’s disease: from the Global Parkinson’s Genetics Program

    GP2. Parkinson'S_genetics_program (gp2) (Chevy Chase, USA)

    Objective: To investigate chromosome X genetic risk factors for Parkinson's disease (PD) across European ancestries (European, Ashkenazi Jewish, Finnish) using data from the Global Parkinson's…
  • 2025 International Congress

    Efficacy and Safety of Fecal Microbiota Transplantation in the Management of Parkinson’s Disease: A Systematic Review

    Y. Abdalla, A. Hassan (Zagazig, Egypt)

    Objective: 1. Assess the efficacy of FMT in PD by evaluating its impact on motor and non-motor symptoms.2. Determine the safety profile of FMT in…
  • 2025 International Congress

    Efficacy and outcomes of deep brain stimulation in elderly Parkinson’s disease: An institutional based study

    M. Karri, R. Kandadai, R. Borgohain, S. Kola, R. Alugolu, P. Vvsrk, T. Syed, S. Mohareer, Y. Kancharla (Hyderabad, India)

    Objective: Advanced therapies like DBS have been approved modalities for PD. Most studies focused on age below 65, reporting improvement in motor symptoms with persistent…
  • 2025 International Congress

    Deep Brain Stimulation for Early-Onset Parkinson’s Disease: A Systematic Review and Meta-Analysis

    K. Acurio-Ortiz, M. Hemeryth-Rengifo, G. Quispe-Villegas, F. Váscones-Román, V. Abuid-Sampelayo, D. Salazar-Flores, C. Quispe-Vicuña, A. Flores-Gavino, B. Avila-Lucas, M. Vilca-Salas, N. Pacheco-Barrios (Lima, Peru)

    Objective: To evaluate clinical outcomes in patients with Early-Onset Parkinson’s Disease (EOPD) treated with deep brain stimulation (DBS) Background: EOPD is defined as Parkinson’s disease…
  • 2025 International Congress

    Effectiveness and Outcomes of Deep Brain Stimulation revision surgery for Parkinson’s Disease

    MG. Choi, SY. Jo, JH. Lee, SJ. Chung (Goyang-si, Republic of Korea)

    Objective: This study investigated the clinical characteristics, therapeutic efficacy and postoperative outcomes of Parkinson’s disease (PD) patients undergoing deep brain stimulation (DBS) revision surgery Background:…
  • 2025 International Congress

    Association between corneal sensitivity with vision-related quality of life and ocular surface symptoms in Parkinson’s disease

    A. Camacho-Ordonez, M. Navarrete-Azuara, GR. Vera-Duarte, M. Rodriguez-Violante, A. Cervantes-Arriaga, AG. Alcocer-Salas, A. Ramirez-Miranda, EO. Graue-Hernandez (Mexico, Mexico)

    Objective: To evaluate the association between corneal sensitivity (CS) as measured by a non-contact Brill Engines esthesiometer, vision-related quality of life and ocular surface symptoms…
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