The Protective Role of Lysosomal Damage Response in Preventing α-Synuclein Propagation
Objective: The aim of this study was to investigate the mechanism by which the lysosomal damage response (LDR) defends against the escape of α-synuclein (αSyn)…Measures of Mitochondrial Function in Serum across the Parkinson’s Disease Spectrum
Objective: To resolve the inconsistencies in the magnitude and type of mitochondrial dysfunction within peripheral blood mononuclear cells (PBMCs) from people with Parkinson’s disease (PD),…Association of Retinol Binding Protein (RBP) and the Risk of Parkinson’s disease (PD): A Narrative Literature Review
Objective: This review aimed to investigate the association between RBP levels and the risk of Parkinson’s disease Background: RBP facilitates retinol transport from the liver…Association of Striatal Dopaminergic Depletion, Cerebral Perfusion, and Cognitive Outcome in Brain-first and Body-first Parkinson’s Disease
Objective: This study investigated whether brain-first and body-first Parkinson’s disease (PD) showed different pattern of subregional striatal dopamine loss and cerebral perfusion using dual-phase 18F-FP-CIT…Neural Correlates of Dual Task Touchscreen Performance in Parkinson’s Disease
Objective: To compare task-related brain activity during a touchscreen task in Parkinson’s disease (PD) patients and healthy controls (HC) in single (ST) and dual task…Comparison of Spontaneous Brain Activity in Distinguishing Parkinsonian Variant of Multiple System Atrophy from Parkinson’s Disease at Early Stage
Objective: The primary objective was to explore distinctions in the fractional amplitude of low-frequency fluctuation (fALFF) indicator among early-stage parkinsonian variant of multiple system atrophy…Association Between Cerebral Glucose Metabolism and Amyloid Deposition in Parkinson’s Disease
Objective: To investigate the potential association between cerebral amyloid (Aβ) deposition and regional brain metabolism in patients with Parkinson's disease (PD) Background: Although Parkinson's disease (PD)…Comparative Study of Whole-Brain Functional Connectivity Patterns in Parkinson’s Disease and Essential Tremor: A Resting-State fMRI Study
Objective: Our study aimed to analyze the alterations in brain FC in subjects with tremor-dominant PD compared to ET subjects. Background: While both tremor-dominant Parkinson’s…The Impact of Bilateral STN- Deep Brain Stimulation on Motor Symptoms and Quality Of Life in Advanced Parkinson’s Disease: A Single Center’s Experience
Objective: The aim of this study was to examine the effects of bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) on motor symptoms and quality…Ethnic and Gender Disparities in Access to Deep Brain Stimulation: A Qualitative Exploration
Objective: The objective of this qualitative inquiry is to explore the experiences of people with movement disorders in terms of ethnic and gender-related barriers to…
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