Characteristics and Trends of Parkinson’s Disease Patients Receiving Deep Brain Stimulation: Insights From a US All-Payer Health Administrative Claims Database
Objective: To describe sociodemographics, treatment patterns, and costs among Parkinson’s patients who received deep brain stimulation (DBS) in the United States (US). Background: Parkinson’s disease…Prevalence of Central Pain in Parkinson’s Disease: A Systematic Review and Meta-analysis
Objective: In this systematic review and meta-analysis, we aimed to evaluate the prevalence of central pain and how this symptom may affect the patient's quality…Exploring the ubiquitome in Parkinson’s Disease
Objective: To explore the role of ubiquitin signalling defects in Parkinson’s Disease. Background: Defects in ubiquitin signalling have been implicated in the pathogenesis of neurodegenerative…Apolipoprotein E ɛ4-allele and Amygdala Atrophy in Parkinson’s Disease: A Preliminary Longitudinal Analysis from the ONDRI Cohort
Objective: To investigate the association of apolipoprotein E ɛ4-allele (APOE-ε4) with amygdala volumes longitudinally in Parkinson’s disease (PD). Background: APOE-ε4 is a genetic risk factor…Contribution of Dopamine Depletion, Cerebral Perfusion, and Cognition to Gait Dysfunction in Parkinson’s Disease
Objective: To explore the potential contribution of dopamine loss, perfusion deficit, and cognition to spatiotemporal gait parameters in patients with Parkinson's disease (PD). Background: Gait…Comparison of Microglial PET Imaging in Parkinson’s Disease, RBD, and Controls with a CSF1R and TSPO Ligand.
Objective: To compare regional binding patterns of microglial PET radioligands: [11C]DPA-713, a TSPO ligand, and [11C]CPPC1, a CSF1R ligand in people with Parkinson’s disease (PD).…Cerebello-Thalamo-Cortical Tract Microstructural Changes in Parkinson’s Disease Patients with Tremor
Objective: To evaluate microstructural characteristics in the cerebello-thalamo-cortical circuit (CTC) of Parkinson's Disease (PD) patients with different tremor phenotypes. Background: Tremor is one of the…Description Genotype/phenotype of patients with Parkinson’s disease. Report of an Argentinean cohort included in the LARGE PD Consortium.
Objective: To characterize the genetic and phenotypic profile of Argentinean Parkinson's patients and contribute to the understanding of the genetic heterogeneity of this disease. Background:…Investigating the Global Genetic Spectrum of Monogenic Parkinson’s Disease and Parkinsonism
Objective: To investigate known pathogenic and risk variants linked to Parkinson’s disease (PD) at a global, multi-ancestry scale. Background: Genetic forms of PD have been…Non-motor Symptoms, Sleep Disturbances, And Genetic Insights In Young Onset Parkinson’s Disease: A Prospective Descriptive Study
Objective: 1. To study the prevalence of various non-motor symptoms in Young onset Parkinson's Disease patients2. To study the genetic markers in YOPD patients. Background:…
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