Opicapone for OFF Motor Fluctuations in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Trials
Objective: To evaluate the efficacy of opicapone 50 mg in reducing OFF time and improving motor function in Parkinson’s disease (PD) patients with motor fluctuations.…Continuous Subcutaneous Dopaminergic Stimulation: Exploring the impact of Foslevodopa/Foscarbidopa on Gait in Parkinson’s disease.
Objective: The primary objective of this study is to investigate the effect of continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa (FL/FC) on gait in those with…Mortality and Institutionalisation Following de Novo Use of Rotigotine Patches in Hospitalised Patients with Parkinson’s Disease
Objective: Guidelines recommend use of rotigotine patches as an option if Parkinson’s patients are unable to take their usual oral medication, but this strategy has…Motor Fluctuations in Parkinsons Disease and their Correction
Objective: To evaluate the frequency of motor fluctuations in patients with Parkinson's disease and to study the effectiveness of methods modifying the course of the…Diagnostic accuracy and clinical correlates of real-time quaking-induced conversion assay on gastric biopsy in early Parkinson’s disease
Objective: To evaluate the utility of the real-time quaking-induced conversion (RT-QuIC) assay in stomach biopsies as a biomarker for early Parkinson’s disease (PD) and to…Sex Differences in α-Synuclein Seed Amplification Assay Parameters and Longitudinal Clinical Subtypes of Parkinson’s Disease
Objective: To investigate differences in baseline α-synuclein seed amplification assay (SAA) metrics and longitudinal clinical subtypes of Parkinson’s disease (PD) between the two biological sexes.…AntiSaccadeNet: A Deep Learning Framework for Differentiating Parkinsonian Disorders through Antisaccade Time Series Classification
Objective: To develop and evaluate a deep learning architecture (AntiSaccadeNet) that utilizes continuous antisaccade eye movement time-series data to differentiate between Parkinson's disease (PD) and…Virtual Reality to Assess for Digital Biomarkers of Visual Hallucinations in Parkinson’s Disease
Objective: Use a novel virtual reality (VR) protocol to evaluate for potential digital biomarkers of visual hallucinations (VH) in Parkinson’s Disease (PD). Background: VH are common…Advancing the regulatory maturity of digital health technologies with focus on early intervention, Critical Path for Parkinson’s 3DT initiative
Objective: To report the feedback from global regulatory agencies to Critical Path Institute (C-Path) on the use of digital health technologies (DHTs) for Parkinson’s disease…Effect of Systematic Survey-based Screening for Depression in Parkinson’s Disease
Objective: To determine the impact of systematic survey-based screening for depression on treatment outcomes in people with Parkinson's disease (PD) in a clinical practice setting. Background: Depression in…
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