Unraveling Parkinson’s Disease Heterogeneity: Variability in Dopaminergic Medication Response Over Five Years – A Cluster Analysis of PPMI Data
Objective: We sought to examine which demographic, genetic, and clinical characteristics inParkinson’s disease (PD) are associated with differences in levodopa equivalent daily dose(LEDD) at five…Developing Competency-Based Training Modules for Health Professionals in Parkinson’s Disease Management: A Review of Current Practices and Future Needs
Objective: To review existing competency-based training programs for health professionals in Parkinson’s disease (PD) management and identify future educational needs to enhance patient care. Background:…Effect of Virtual Rehabilitation Therapy on Patients with Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To assess the efficacy of virtual rehabilitation therapy compared to conventional physical therapy in patients with Parkinson’s disease. Background: Rehabilitation is essential in managing…Association Between Trait Impulsivity and Freezing of Gait in People with Parkinson’s Disease
Objective: To analyze the association between motor, attentional and non-planning impulsivity and freezing of gait in people with PD Background: Freezing of gait is a…Quality of Life of Parkinson’s Disease Patients in the Thai Population: A Cross-Sectional Analysis
Objective: Primary: To assess QoL in PD patients at the Neurological Institute of Thailand (NIT).Secondary: To identify clinical factors associated with QoL. Background: Parkinson’s disease…Negative Correlation between Apathy and Executive Functioning in Patients with Idiopathic Parkinson’s Disease without Dementia.
Objective: To establish the impact of apathy on executive functioning in patients with IPDWD. Background: Executive Functioning is one of the domains of neurocognitive functioning…Modeling Inflammation in GBA-Associated Parkinson’s Disease: Insights into Disease Mechanisms
Objective: This investigation centers on the role of inflammation in GBA-associated Parkinson’s disease (PD), a neurodegenerative disorder characterized by the progressive degeneration of dopaminergic neurons,…Cell-type specific bidirectional modulation of STN neurons rescue Parkinsonian motor symptom.
Objective: This study aimed to identify the specific STN cell type and circuit responsible for alleviating parkinsonian motor symptoms through targeted neural modulation. Background: The…Mass spectrometry-based screening for α-synuclein bioactive marine natural products
Objective: This study identifies marine-derived natural products with binding affinity and aggregation-inhibition activity against α-synuclein (α-syn) using a mass spectrometry (MS)-based screening approach. The objective…Characterising Peripheral Innate Immune Cell Infiltration into the Brain in Parkinson’s Disease
Objective: To characterise the infiltration of peripheral innate immune cells (NK cells, monocytes and neutrophils) into the brain in Parkinson’s disease (PD) and to investigate…
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