From Campotomy to MR-Guided Focused Ultrasound Pallidothalamic Tractotomy for Parkinson’s: A Systematic Review in the Context of a Phase III Study
Objective: To summarize and review efficacy and safety evidence of pallidothalamic tractotomy (PTT) using MR-guided focused ultrasound (MRgFUS). Background: Speigel and Wycis performed lesions in…Weight loss post deep brain stimulation to bilateral subthalamic nuclei in a Parkinson’s disease with PARKIN mutation – A Harbinger sign of malignancy
Objective: We present a challenging case of genetic PD who presented with progressive weight loss and constipation despite post-DBS and was found to have malignancy.…Application of Respiratory-Controlled Cardiopulmonary Coupling in Early Diagnosis of Parkinson’s Disease
Objective: Studies have shown that autonomic nervous symptoms precede motor symptoms in PD, making autonomic function assessment a potential tool for early PD diagnosis. This…Exploring the Trade-offs Between Speech and Gait in Parkinson’s Disease
Objective: The goal of the study was to explore speech and gait performance trade-off when individuals with Parkinson’s disease (PD) engaged in concurrent speaking and…Parkinson’s Disease (PD) and Type II Diabetes (T2DM): Risk and Progression
Objective: To test whether PD risk is greater in those with a prior diagnosis of T2DM, and whether T2DM is associated with faster PD clinical…Metabolic network signature of quantitative motor effects following deep brain stimulation in Parkinson’s disease
Objective: To integrate [18F]-FDG PET (fPET) and objective motor performance to unravel metabolic networks associated with deep brain stimulation (DBS) outcomes in Parkinson’s disease (PD).…Automatic Intelligibility Rating in Parkinson’s Disease: A Multilingual Approach
Objective: To investigate the validity and robustness of an automatically generated intelligibility score in Parkinson’s disease (PD) across multiple languages. Background: 90% of people with…Traditional Deep Brain Stimulation Programming versus Automated Image-Guided Algorithm in Patients with Parkinson’s Disease
Objective: To compare traditional initial deep brain stimulation (DBS) programming with artificial intelligence (AI)-assisted automated image-guided DBS programming algorithm. Background: DBS programming is a complex,…Electrochemical Sensing for Accurate L-Dopa Detection in Parkinson’s disease
Objective: This study aims to develop a cost-effective, portable electrochemical sensor for real-time L-dopa monitoring in PD patients, addressing the limitations of current detection techniques.…Expanding the Scope Beyond Neurosurgery: A Systematic Review on MRgFUS Complications
Objective: This systematic review aims to investigate the complications associated with MRgFUS (magnetic resonance-guided high intensity focused ultrasound) for neurological disorders and determine their frequency…
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