Long-Term Effect of Opicapone in Parkinson’s Patients Without Motor Complications: 1.5-year EPSILON Study Findings
Objective: We report motor function, motor complication and tolerability findings of the EPSILON study up to 1.5 years. Background: The 24-week, double-blind, placebo-controlled Phase III…Characterizing the Neural Signature of Parkinsonian Freezing of Gait During an Immersive Virtual Reality Paradigm
Objective: To characterize the neural signature of Freezing of gait (FOG) in Parkinson’s disease (PD) across multiple types of triggers. Background: FOG is among the…Identifying the Prognostic Outcomes of Parkinson’s Patients with Impaired Swallow.
Objective: To identify the prognostic outcomes of patients with Parkinson’s disease (PD) when they are unable to take their oral medication and are medicated via…Effectiveness of Opicapone Added to Different Levodopa Doses and LEDDs in Parkinson’s Disease: Post-Hoc Analysis of the ADOPTION Trials
Objective: To assess the efficacy of opicapone 50 mg, compared to an additional 100 mg dose of levodopa, in reducing OFF-time in Parkinson’s disease (PD)…Risk factors for central nervous system side effects of amantadine
Objective: The purpose of this study was to investigate the threshold blood level of amantadine and risk factors for central nervous system (CNS) side effects…Influence of age at onset on medication profile in patients with Parkinson’s disease: A prospective study from a tertiary care center in India
Objective: To study the effect of age at onset on the medication profile of various Parkinson's disease (PD) related medications. Background: Multiple factors determine the…Therapeutic Effect and Mechanism of Targeted Nano-selenium in Mouse Model of Parkinson’s Disease Induced by MPTP
Objective: In the present study, we developed a nanozyme (Se@PB-ACPP) incorporating selenium-loaded Prussian blue (PB) and modified it with an activatable cell-penetrating peptide (ACPP) to…Monitoring Parkinson’s Disease in the Dental Chair
Objective: Our goal is to bridge the mechanistic knowledge gap on the Microbiota-Gut-Oral-Brain-Axis (MGOBA)’s role in Parkinson’s disease (PD) pathogenesis through a case-control, proof-of-concept, observational…iPad App-based Eye Tracking for the Early Detection of Parkinson’s Disease
Objective: Demonstrate the concurrent validity, diagnostic accuracy, and early detection ability of an iPad app-based eye tracking tool for the early detection of Parkinson’s disease…Associations among blood biomarkers, clinical subtypes, and prognosis in Parkinson’s disease
Objective: The aim of the present study was to test whether plasma NF-L, FABP3, UCH-L1, and gray matter volumes can be used as prognostic biomarkers…
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