A Preliminary Report on the Clinical Profile of People with PD at an Outpatient Clinic in Malawi
Objective: The objective of the study is to analyze the clinical and socio-demographic characteristics of people with Parkinson`s (PwP) attending the adult neurology outpatient clinic…Characterising early morning akinesia and off (EMO) using Parkinson’s kinetigraph: analysis from a two centre national database in Parkinson’s disease .
Objective: Could wearable sensors such as Parkinson’s kinetograph (PKG) may provide valuable overnight data to detect EMO to augment care in clinic. Background: Early morning…Clinical characteristics associated with early discontinuation of Levodopa-Carbidopa Intestinal Gel infusion in patients with advanced Parkinson Disease.
Objective: To determine the clinical characteristics associated with early withdrawal of Levodopa-Carbidopa Intestinal Gel infusion (LCIG) in patients with advanced Parkinson´s Disease (APD) Background: LCIG…Writing rehabilitation in parkinson’s disease (pd) through a virtual workshop
Objective: Evaluate the effect of intensive writing training through a virtual workshop once a week and the potential influence in the quality of life in…Parkin regulates ER-mitochondria association through interaction with IP3R-Grp75-VDAC1
Objective: The objective of this study is to explore how Parkin modulates the interplay between mitochondria and the endoplasmic reticulum (ER), along with elucidating its…Gut Microbial Metabolites and Future Risk of Parkinson’s Disease: A Metabolome-wide Association Study
Objective: To prospectively investigate the association between plasma microbial metabolites and Parkinson’s disease (PD) risk within a metabolomics framework. Background: Gut microbiota is altered in…A Machine Learning Approach for Early Identification of Prodromal Parkinson’s Disease
Objective: The aim of this project is to analyze available data of voice, Tappy keystroke, spiral drawings, and gait sample data involving PD patients and…First in vivo evidence of the role of the noradrenergic system in olfactory dysfunction in Parkinson’s disease
Objective: To investigate the relationship between in vivo noradrenergic markers and olfactory impairment in patients with Parkinson’s disease (PD). Background: Degeneration of the noradrenergic (NA)…Dopamine Transporter Imaging as Monitoring Biomarker in Parkinson’s Disease
Objective: To investigate the longitudinal relationship between changes in dopamine transporter single-photon emission computed tomography (DaT SPECT) and changes in motor symptom severity in Parkinson’s…Data-driven image-based subtyping and staging of neurodegeneration in Parkinson’s disease
Objective: We aimed to conduct image-based, data-driven classification of Parkinson’s disease (PD) progression using event-based modeling (EBM) and derive neuropathological insights from the results. Background:…
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