Integrating Counterclockwise Theory, Mental Imagery, and Art Therapy for Parkinson’s Disease: A Proposed Protocol for Motor and Non-motor Symptom Management
Objective: This review/protocol proposal explores whether combining three concepts Counterclockwise theory, Imagery training, and Art therapy can improve motor symptoms and enhance the quality of…Access to Allied Health Services by People Living with Parkinson’s Disease: A Qualitative Study
Objective: To determine the referral patterns of people with Parkinson’s disease (PwPD) to allied health from their perspective. Background: Allied health interventions can improve impairments…P2P Therapeutics Platform Trial in Stage 2B Neuronal Alpha-Synuclein Disease: Study Design and Statistical Considerations
Objective: To describe the study design and timeline of a platform interventional study in Neuronal α-Synuclein Disease (NSD). Background: The recent description of the biological…Smartphone-based digital assessments in the LUMA trial of BIIB122 for early-stage Parkinson’s disease
Objective: To evaluate the sensitivity of routine smartphone-based performance assessments in the free-living environment as part of a randomized clinical trial in Parkinson’s disease (PD).…Evaluation of Impact of Helicobacter Pylori Eradication on Symptomatology and Quality of Life in Parkinson’s Disease
Objective: This study aimed to determine the effects of Helicobacter Pylori(HP) eradication treatment on motor and non-motor symptoms and quality of life of PD patients…Quality of Life Improvements in Parkinson’s Disease for Those Treated with Photobiomodulation Plus Exercise: A Sham-Controlled Study
Objective: To assess whether exercise alone, or exercise combined with photobiomodulation (PBM) can improve the health-related quality of life (QoL) for people with Parkinson’s disease…Random-Order Crossover Trial Assessing the Safety, Feasibility and Exploratory Efficacy of Two Mediterranean-Ketogenic Nutritional Interventions in Parkinson’s Disease
Objective: Assess the feasibility, safety and exploratory efficacy of two Mediterranean-ketogenic dietary interventions in individuals with Parkinson’s disease (PD). Background: Both Mediterranean and ketogenic diets…A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of the NLRP3 Inhibitor Vent-02 in Patients with Mild to Moderate Parkinson’s Disease
Objective: To describe the innovative Phase 2 study design aimed to investigate vent-02 in the treatment of PD. Background: NLRP3 hyperactivation plays a critical role…Ferritin-related Brain Iron Deposition in Parkinson’s Disease Involves α-Synuclein Pathology
Objective: To investigate plasma neuron-derived ferritin-containing extracellular vesicles (NDFEVs) differences between Parkinson’s disease (PD) patients and controls, assess their association with brain iron deposition, and explore the…The neuroprotective effects of Echinacoside on α-synuclein fibril-induced Parkinson’s disease mice model
Objective: This study further investigates the ameliorative effects of ECH on neurobehavioral abnormalities and nigrostriatal dopaminergic system impairment in α-synuclein preformed fibrils (α-Syn PFFs)-induced PD…
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