Brain first-body first: is the dat-scan useful?
Objective: The purpose of this study is to evaluate possible differences in the DAT-SCAN ratios in patients with and without dysautonomia and RBD at diagnosis.…Correlation between Striatal degeneration and Cerebellar fiber alterations of Parkinson’s disease
Objective: We tried to show divisional evaluation of caudate and putamen in [123I] FP-CIT(DAT) -SPECT has use for assessment of PD symptoms and capture the…Radiological markers of CSF α-synuclein aggregation in Parkinson’s disease patients
Objective: To investigate the association between cerebrospinal (CSF) αS aggregates, MRI, and dopamine transporter spectral tomography (DaTscanTM) imaging metrics. Background: Synuclein amplification assays (SAA) enables…Genetic polymorphisms associated with nigrostriatal dopaminergic depletion as measured with [I123]-FP-CIT SPECT in Parkinson’s disease
Objective: To conduct a genome-wide association study (GWAS) of striatal [I123]-FP-CIT SPECT signal as endophenotype to explore possible associations between genetic background and nigrostriatal dopaminergic…An in-vivo study of the integrity of the nigrostriatal pathways in drug-naive Parkinson’s disease patients using [11C]PE2I PET and neuromelanin-Magnetic Resonance Imaging
Objective: This study evaluated the relationship between the neurodegeneration of the substantia nigra neurons, assessed using Neuromelanin-sensitive MRI, and of the loss of striatal dopaminergic…Insular dopamine deficits in prodromal α-synucleinopathies
Objective: aim of the study was to evaluate the dopamine binding characterizing subjects both at prodromal and symptomatic stages in α-synucleinopathies, by means of ROI-based…Education and the motor effects of dopamine loss in Parkinson’s disease
Objective: To examine the relation between education and dopamine signal loss in PD. Background: In support of the cognitive reserve concept, it has consistently been…Artificial intelligence for the improvement of imaging biomarkers in Parkinson’s disease
Objective: To systematically review the current literature on the application of artificial intelligence (AI) for imaging biomarkers in Parkinson's disease (PD) and to identify translational…Gerstmann-Straussler-Scheinker Syndrome Manifesting Levodopa-Responsive Parkinsonism, Levodopa-Induced Dyskinesia, and Abnormal DaT-SPECT
Objective: The objective of this report is to describe previously unreported features in a patient with Gerstmann-Straussler-Scheinker syndrome (GSS) due to the F198S mutation. Background:…Correlation between 3 Tesla Brain MRI Nigrosome-1 imaging and SPECT 123I-Ioflupane in parkinsonian disorders
Objective: To correlate nigrosome-1 (NG1) imaging and SPECT 123I-Ioflopane findings to determine the feasibility and diagnostic value of NG1 imaging in a real-world clinical setting.…
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