Rest Tremor in Parkinson’s Disease Is Associated with Increased Ipsilateral DAT Binding
Objective: To investigate the connection between striatal dopamine transporter binding and cardinal motor symptoms of Parkinson’s disease. Background: The three cardinal motor symptoms of Parkinson’s…Increased free water in the putamen in idiopathic REM sleep behaviour disorder
Objective: This study aimed to evaluate the free water in the dorsoposterior putamen of idiopathic REM sleep behaviour disorder (iRBD) patients, which is considered a…Hemiparkinsonism secondary to a cerebral cavernous malformation (CCM)
Objective: To describe a case of secondary parkinsonism of unhabitual cause and complex treatment. Background: Secondary parkinsonism constitutes approximately 15% of all parkinsonism cases in…Neurophysiological markers of motor reserve in Parkinson’s disease
Objective: Our objective was to investigate Motor Reserve (MR) in idiopathic Parkinson’s Disease (PD). Background: MR is defined as the resilience mechanisms of the brain…Brain first-body first: is the dat-scan useful?
Objective: The purpose of this study is to evaluate possible differences in the DAT-SCAN ratios in patients with and without dysautonomia and RBD at diagnosis.…Correlation between Striatal degeneration and Cerebellar fiber alterations of Parkinson’s disease
Objective: We tried to show divisional evaluation of caudate and putamen in [123I] FP-CIT(DAT) -SPECT has use for assessment of PD symptoms and capture the…Radiological markers of CSF α-synuclein aggregation in Parkinson’s disease patients
Objective: To investigate the association between cerebrospinal (CSF) αS aggregates, MRI, and dopamine transporter spectral tomography (DaTscanTM) imaging metrics. Background: Synuclein amplification assays (SAA) enables…Genetic polymorphisms associated with nigrostriatal dopaminergic depletion as measured with [I123]-FP-CIT SPECT in Parkinson’s disease
Objective: To conduct a genome-wide association study (GWAS) of striatal [I123]-FP-CIT SPECT signal as endophenotype to explore possible associations between genetic background and nigrostriatal dopaminergic…Investigating the use of DAT-SPECT as an enrichment biomarker to determine eligibility for the phase 2 clinical trial PASADENA
Objective: Evaluate dopaminergic imaging DAT-SPECT as an enrichment strategy to avoid inclusion of participants with scans without evidence of dopaminergic deficit (SWEDD) in a Phase…Neuroimaging in Glucocerebrosidase-associated parkinsonism: a systematic review
Objective: To critically review studies applying neuroimaging to Glucocerebrosidase (GBA)-associated parkinsonism. Background: Mutations in the GBA gene cause Gaucher disease (GD) and constitute the most…
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