Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders
Objective: We test the hypothesis of modulating subthalamic neuronal firing pattern via injection of hyperpolarizing current as an effective treatment for hyperkinetic movement disorders. Background:…Real World Clinical Outcomes Using a Novel Directional Lead from a Multicenter Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: In this report, initial real-world outcomes using a directional lead with a deep brain stimulation (DBS) system capable of multiple independent current source control…High-Beta and High-Gamma Power Oscillations from Subthalamic Nucleus distinguishes Parkinson’s Disease Subtypes
Objective: To distinguish Parkinson’s disease (PD) subtypes – tremor dominant (TD) and Akinetic-rigid (AR) – by means of local field potentials spectral features recorded from…Long term outcome of STN-DBS for Parkinson Disease patients using Directional mode setting programs
Objective: To survey the long term effectiveness of the directional mode setting programs for Parkinson Disease patients with Subthalamic Deep Brain Stimulation (STN-DBS). Background: Background:…Directional lead local field potentials show distinct spatial resolution
Objective: To characterize the spatio-spectral patterns of local field potentials (LFPs) in the subthalamic nucleus (STN) recorded from segmented DBS electrodes. Background: PD patients in…Local anesthesia vs general anesthesia in STN-dDBS operation: a clinical comparison of the outcome of patients with advanced Parkinson’s disease
Objective: To compare clinical outcome of patients with Parkinson’s disease (PD) treated with directional deep brain (dDBS) stimulation undergoing subthalamic deep brain stimulation operation (STN-DBS)…Local beta band synchronization predicts clinically-selected deep brain stimulation contact in Parkinson’s disease patients
Objective: To determine whether local field potential (LFP) recordings from segmented deep brain stimulation (DBS) leads in the subthalamic nucleus (STN) and the globus pallidus…Long-term follow up of unilateral focused ultrasound subthalamotomy for the treatment of motor features in asymmetric PD
Objective: To report long-term outcome of unilateral MR-guided focused ultrasound(MRgFUS) subthalamotomy for the treatment of PD cardinal motor features. Background: The development of MRgFUS as…No evidence for early emotional processing in the subthalamic nucleus – a single neuron study
Objective: To provide evidence of early emotional processing at the single-neuron level in the STN. Background: A fast response to coarse threat signals in the…Cognitive outcomes of STN-DBS in GBA mutation carriers with PD
Objective: To determine the rate of cognitive decline in glucocerebrosidase (GBA) mutation carriers with subthalamic nucleus deep brain stimulation (STN-DBS). Background: About 12-17% of Parkinson’s…
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