APOE-ɛ4 status and cognitive decline after subthalamic nucleus-deep brain stimulation in Parkinson’s disease: preliminary results of the GENEPARK-DBS study
Objective: The aim of this study was to evaluate wheter the presence of APOE-ε4 in a cohort of Parkinson’s disease (PD) patients treated with subthalamic…Theoretical Definition of DBS Electrode Misplacement
Objective: To propose a definition of Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) electrode misplacement (MP) based on ideal brain connectivity strength. Background: MP is defined…Deep brain stimulation impacts functional brain connectivity in Parkinson’s disease.
Objective: Deep-brain stimulation (DBS) became a successful method to treat Parkinson’s disease (PD), particularly with stimulating the subthalamic nucleus (STN-DBS), although the precise mechanisms mediating…Tremor characteristics differentially respond to levodopa and subthalamic nucleus deep brain stimulation in Parkinson’s disease
Objective: To identify factors predictive of responsiveness of tremor to levodopa and STN-DBS. Background: Tremor in Parkinson’s disease (PD) is phenotypically variable and has an…Directional deep brain stimulation therapy in the long term
Objective: To describe our long-term clinical experience with directional deep brain stimulation (d-DBS) in patients with advanced Parkinson’s disease (PD) who have been implanted with…Effects of GBA1 mutations and STN-DBS on response inhibition in Parkinson’s disease
Objective: To determine specific pattern of cognitive dysfunction in Parkinson’s disease (PD) patients who are glucocerebrosidase mutation carriers (PD-GBA1) compared with non-mutation carriers with and…Clinical accuracy of Medtronic’s Percept built in longevity estimate algorithm following device exchange.
Objective: To examine the accuracy of Medtronic’s Percept built in device longevity estimate. Background: In June of 2020 Medtronic received FDA approval for its Percept…Does beta band activity correlate with electrode location within the STN in postoperative processed images?
Objective: To identify the best tool for guidance in an initial programming of deep brain stimulation (DBS).To explore the potential correlation between postoperative images created…Emergent alpha-beta oscillations are accompanied with worsening motor symptoms in Parkinson’s disease
Objective: The aim of the study was to imply observer-independent approach to search for the ranges of stable oscillations in broad alpha-beta range inside the…Deep brain stimulation and fusion technologies: a synthesis study
Objective: The major thrust is analyzing the large amounts data computationally generated and synthesizing it into useful systems-wide models of biological processes. Background: It is…
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