Tau Deposition in Locus Coeruleus is Associated with Rapid Eye Movement Sleep Behavior Disorder in Progressive Supranuclear Palsy.
Objective: In this study, we aimed to investigate the frequency of Rapid eye movement sleep behavior disorder (RBD) occurring in a large cohort of PSP,…Longitudinal progress and clinical relevance of 18F-Florzolutau PET in patients with PSP: a one-year follow-up study
Objective: Here we aimed to explore the progress of 18F-Florzolotau PET and its clinical relevance in patients with PSP during one-year follow-up. Background: The 18F-Florzolotau…Clinical and neuroimaging factors associated with survival in Progressive Supranuclear Palsy
Objective: To assess clinical and neuroimaging factors associated with survival in a cohort of patients with a final clinical diagnosis of Progressive Supranuclear Palsy (PSP)…Development and Validation of a Clinical Scale for Distinguishing Multiple System Atrophy from 4-Repeat Tauopathies
Objective: We aimed to develop a clinical scale that distinguishes between Multiple System Atrophy (MSA) and 4-repeat tauopathies (4RT: CBD, PSP) using a standardized neurological…Phenotypic characterization of 104 patients with Progressive Supranuclear Palsy: A Tertiary care experience from South India
Objective: To prospectively evaluate and subtype the patients of Progressive supranuclear palsy being referred to a tertiary care movement disorders facility in South India. Background:…Early-onset cortico-basal degeneration (CBD) due to a c.2092G>A MAPT mutation
Objective: To describe a patient with early-onset atypical parkinsonism that evolved to a classic CBD without dementia, associated to a c.2092G>A MAPT mutation Background: Although…Cell-specific MAPT gene expression is preserved in tau cytopathologies in Progressive Supranuclear Palsy
Objective: To systematically map and quantify MAPT expression in neurons, astrocytes and oligodendroglia across different brain regions to determine whether cell type and/or regional differences…Structural analysis of the basal ganglia using ex vivo 7T MRI can differentiate frontotemporal lobar degeneration with TDP-43 vs tau accumulation.
Objective: Ex vivo 7T MRI can identify macrostructural changes in the basal ganglia that reflect underlying neuropathology, and can be used to differentiate between proteinopathies…18f-PI-2620 tau PET neuroimaging, tau protein burden and 18f-PI-2620 tau autoradiography on human postmortem brain tissue in a PSP patient
Objective: Our aim is to describe the findings of 18F-PI-2620 tau-PET imaging, together with tau protein burden and 18F-PI-2620 tau autoradiography in brain tissue from…Clinico-pathological correlations in atypical parkinsonism
Objective: We aim to assess diagnostic accuracy of the Parkinson-plus syndromes (PPS) using the current consensus criteria, whilst identifying the diagnostically most salient clinical features.…
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