Introducing the molecular subtyping of Progressive Supranuclear Palsy: a proof of concept
Objective: To enhance understanding of the molecular mechanisms underlying disease heterogeneity in Progressive supranuclear palsy (PSP) Background: PSP is a 4R-tauopathy characterised by subcortical pathology…Transferrin as a possible CSF biomarker in neurodegenerative proteinopathies
Objective: The aim of this study was to determine whether cerebrospinal fluid (CSF) levels of transferrin differ between patients with Parkinson´s disease (PD), multiple system…Phenotypic characterization of 104 patients with Progressive Supranuclear Palsy: A Tertiary care experience from South India
Objective: To prospectively evaluate and subtype the patients of Progressive supranuclear palsy being referred to a tertiary care movement disorders facility in South India. Background:…Early-onset cortico-basal degeneration (CBD) due to a c.2092G>A MAPT mutation
Objective: To describe a patient with early-onset atypical parkinsonism that evolved to a classic CBD without dementia, associated to a c.2092G>A MAPT mutation Background: Although…Complications in Patients with Progressive Supranuclear Palsy
Objective: This study elucidated the incidence and features of complications in patients with progressive supranuclear palsy (PSP). Background: PSP is a progressive neurodegenerative disorder accompanied…Pan India Registry for Progressive Supranuclear Palsy (PAIR-PSP)
Objective: To understand Progressive Supranuclear palsy (PSP) phenotype and genotype from India. Background: Insights into PSP pathophysiology and newer clinical phenotypes are increasingly being recognized.…Plasma p-tau181 is increased in Lewy body dementia and relates to cognitive performance
Objective: To compare plasma p-tau181 concentration in Parkinson’s disease (PD), Lewy body dementia (LBD) and healthy controls and to examine the relationship between ptau-181 concentration…In-vivo measurement of tau depositions in anti-IgLON5 disease with 18F-PI2620-PET
Objective: The aim of the study was to examine the potential of the second-generation tau-PET tracer 18F-PI2620 to detect tau deposition in anti-IgLON5 disease. Background:…Three patients with PSP presenting with a logopenic pattern of aphasia: expanding the phenotype of language impairment in PSP.
Objective: To investigate the a series of cases presenting with apparent logopenic variant primary progressive aphasia who then developed symptoms suggestive of PSP. Background: Deficits…Neuropathological profile of tauopathy in spinocerebellar ataxia type 8
Objective: The purpose of this study is to examine the distribution of tau pathology in brain regions of patients with spinocerebellar ataxia type 8 (SCA8).…
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