MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2017 International Congress

    Deutetrabenazine is Associated with an Improvement in Involuntary Movements in Patients With Tardive Dyskinesia as Seen by the High Proportion of Responders to Deutetrabenazine Treatment in the AIM-TD Study

    J. Jimenez-Shahed, H. Fernandez, D. Stamler, M. Davis, S. Factor, R. Hauser, J. Isojärvi, W. Ondo, K. Anderson (Houston, TX, USA)

    Objective: To examine response rates between patients receiving deutetrabenazine and placebo. Response levels were pre-specified from 10–90% improvement from baseline in Abnormal Involuntary Movement Scale…
  • 2017 International Congress

    Addressing Involuntary Movements in Tardive Dyskinesia (AIM-TD): Improvements in Clinical Global Impression of Change (CGIC) with Deutetrabenazine Treatment in Tardive Dyskinesia (TD)

    J. Jimenez-Shahed, H. Fernandez, R. Hauser, M. Davis, S. Factor, J. Isojärvi, W. Ondo, D. Stamler, K. Anderson (Houston, TX, USA)

    Objective: To determine the efficacy of deutetrabenazine in patients with TD as measured by CGIC. Background: TD is often irreversible and can affect any body…
  • 2017 International Congress

    Estimation of Tardive Dyskinesia Incidence and Prevalence in the United States

    A. Dhir, T. Schilling, V. Abler, R. Potluri, B. Carroll (New York, NY, USA)

    Objective: To estimate the current and expected epidemiology of tardive dyskinesia (TD) in the United States (US), stratified by level of severity. Background: TD is…
  • 2017 International Congress

    Effect of Deutetrabenazine by Body Region Score of the Abnormal Involuntary Movement Scale in Tardive Dyskinesia: ARM-TD and AIM-TD Studies

    H. Fernandez, D. Stamler, M. Davis, S. Factor, R. Hauser, J. Isojärvi, L. Jarskog, J. Jimenez-Shahed, R. Kumar, S. Ochudlo, W. Ondo, K. Anderson (Cleveland, OH, USA)

    Objective: To assess the efficacy and safety of deutetrabenazine (DTB) in reducing the severity of the abnormal involuntary movements of tardive dyskinesia (TD) based on…
  • 2017 International Congress

    Healthcare Utilization and Costs for Patients With Tardive Dyskinesia

    B. Carroll, T. Park, D. Irwin, S. Gandhi (Frazer, PA, USA)

    Objective: To assess healthcare utilization and costs pre- and post-tardive dyskinesia (TD) diagnosis in a sample of patients from the commercially insured and Medicare Supplemental…
  • 2017 International Congress

    Addressing Involuntary Movements in Tardive Dyskinesia (AIM-TD): Efficacy, Safety, and Tolerability of Fixed-Dose Deutetrabenazine for the Treatment of Tardive Dyskinesia

    K. Anderson, D. Stamler, M. Davis, S. Factor, R. Hauser, J. Isojärvi, J. Jimenez-Shahed, W. Ondo, H. Fernandez (Washington, DC, USA)

    Objective: To evaluate the efficacy, safety, and tolerability of deutetrabenazine in patients with tardive dyskinesia (TD). Background: AIM-TD is the second large 12-week, Phase III,…
  • 2017 International Congress

    Dopamine Agonists and Postural Disorders in Parkinson’s disease

    L. Ameghino, V. Bruno, M. Merello (Buenos Aires, Argentina)

    Objective: To evaluate the relationship between treatment with DA and the development of postural disorders (CC, PS and AC) in patients with PD.  Background: Stood…
  • 2017 International Congress

    Imbalance between dopaminergic and cholinergic neurotransmission following rotenone administration suggestive of Parkinson’s-like symptoms in male rats

    S. Madiha, S. Haider (Karachi, Pakistan)

    Objective: In the present study we analyzed rotenone-induced gait abnormalities, muscular weakness and locomotor deficits in rats. The study also evaluated the effects of rotenone…
  • 2017 International Congress

    Substantia nigra hyperechogenicity in male methamphetamine users

    G. Todd, V. Pearson-Dennett, B. Collie, J. White (Adelaide, Australia)

    Objective: To investigate the effect of sex on substantia nigra (SN) echogenicity in young-to-middle aged adults with a history of methamphetamine use. Background: The sonographic…
  • 2017 International Congress

    Motor dysfunctions in rats following repeated exposure to stress on the neurotoxicity of lambda-cyhalothrin

    R. Shukla, R. Gupta, A. Pant, V. Khanna (Lucknow, India)

    Objective: To investigate the targets associated in regulating motor functions following subsequent exposure to stress on the neurotoxicity of lambda-cyhalothrin in rats. Background: Stress that…
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