Dual-task gait digital assessment unmask the association between dopaminergic deficits and gait parameters in early and prodromal Parkinson’s Disease
Objective: to explore the relationship between dopaminergic deficits and digital gait parameters alterations in de novo PD and iRBD Background: gait alterations are common features…A Phase 2 Study of Risvodetinib in Untreated Parkinson’s Disease
Objective: Risvodetinib was evaluated in a randomized, double-blind, placebo controlled Phase 2 trial at three doses to determine the safety and tolerability in patients with…Investigating the Neuroprotective Potential of Mushroom Extracts in Parkinson’s Disease In Vitro Models
Objective: This study aims to evaluate the neuroprotective potential of various mushroom extracts in in vitro models of PD. Background: Parkinson’s disease (PD) is a…GBA Mutations Alter Subthalamic and Nigral Neural Activity in Parkinson’s Disease
Objective: To investigate the neurophysiological basis of Parkinson’s disease (PD) in patients with glucocerebrosidase (GBA) mutations. Background: Alterations in subthalamic neural activity are associated with…Coping with Parkinson’s Disease through the Lens of Personality Systems Interactions (PSI) Theory: Two Case Studies
Objective: This study examines how concepts from motivation and personality research contribute to understanding coping strategies in individuals with Parkinson’s disease (PD). Background: Effective treatment…Anterior Pallidal Stimulation for Severe Tourette Syndrome: Open Phase Outcomes
Objective: To present the open phase outcomes of a trial of anterior pallidal stimulation (antGPi DBS) on tic severity in patients with severe Tourette syndrome…The A53T mutation in alpha-synuclein impairs astrocytic metabolism and inflammatory response
Objective: This study aims to explore the impact of the A53T alpha-synuclein (α-syn) mutation on astrocytic homeostasis and metabolism in the presence of inflammatory stimuli.…Traumatic DBS Implant exposure following head injury and its management – a case report.
Objective: To present management plan employed in treatment of a case of traumatic exposure of lead wires in a known case of Idiopathic Parkinson’s disease(PD)…Differentiated approach to treatment and diagnosis of Parkinson’s disease.
Objective: The anatomical and physiological characteristics of tremor in patients with Parkinson’s disease and essential tremor at the same age significantly influence diagnostic approaches, differentiation…PADOVA: Topline results from a Phase IIb study of prasinezumab in early-stage Parkinson’s disease participants on stable symptomatic treatment
Objective: To evaluate the effect of prasinezumab on slowing down disease progression in participants with early-stage Parkinson’s disease (PD) on stable symptomatic medication. Background: Prasinezumab…
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