Multimodal neuroimaging of Parkinson’s disease with diffusion tensor imaging (DTI) and dopamine transporter (DAT) positron emission tomography
Objective: The main aims of this study were to characterize brain microstructure alterations in a cross-sectional cohort of Parkinson’s disease (PD) with DTI and assess…Technological visuo-cognitive training in Parkinson’s disease: Preliminary findings from a pilot randomised controlled trial
Objective: To determine the feasibility and preliminary efficacy of a home-based, technological visuo-cognitive training (TVT) intervention using a mobile application and exercise with stroboscopic glasses…Update on the ADOPTION Study: Randomised, Open-Label Exploratory Trial of Opicapone in Parkinson’s Disease
Objective: This exploratory trial aims to compare treatment outcomes of adding one daily dose of opicapone (OPC) 50 mg versus an additional dose of levodopa…Digital mobility sub-study in the Parkinson’s Progressive Marker Initiative (PPMI) study.
Objective: To test the feasibility and validity of digital mobility data for enrichment of the prodromal screening and to assess the sensitivity of these measures…Progression of the Clinical Features of Progressive Supranuclear Palsy-Richardson Syndrome in Early and Advanced Stages
Objective: We sought to evaluate PSP-Richardson syndrome (PSP-RS) for uniformity of progression over nearly the entire disease course. Rather than comparing scores to the simple…The value of volume of the subthalamic nucleus in diagnosis of progressive supranuclear palsy
Objective: To investigate the diagnostic accuracy of STN volume in PSP using quantitative susceptibility mapping (QSM) imaging and 3T MRI. Background: Various MRI markers are…Comparative Assessment of Gait and Balance in Patients with Parkinson’s Disease and Normal Pressure Hydrocephalus
Objective: Parkinson's disease (PD) and normal pressure hydrocephalus (NPH) cause gait and balance problems, which often lead to falls. The mechanisms responsible for gait and…Stability and predictability of motor symptom control in patients with advanced Parkinson’s disease (aPD) receiving continuous subcutaneous foslevodopa/foscarbidopa (LDP/CDP)
Objective: To evaluate temporal changes in motor states (OFF and ON without troublesome dyskinesia [TD; good ON]) throughout the waking day in patients with aPD…Outcomes From Genetic Testing in a UK Movement Disorder Clinic
Objective: The reported yield from next generation sequencing (NGS) in Movement Disorder clinics is 11.3 – 22% [1,2]. We aimed to determine current practice and yield…Does sleep disorder affect cognitive impairment in Parkinson’s disease?
Objective: The aim of this study was clarified the relationship between cognitive dysfunction and sleep disorders in Parkinson's disease(PD). Background: In PD, cognitive decline increases…
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