Increased cholinergic activity in specific brain regions associated with the presence of dyskinesias in Parkinson’s disease: A [18F]-FEOBV PET study
Objective: To explore the role of cholinergic dysfunction in dyskinesia symptoms in people with Parkinson’s disease (PD). Background: Dyskinesias, involuntary and sometimes excessive or uncontrolled…Association between environmental phthalates exposure and gut microbiota and metabolome in dementia with Lewy bodies
Objective: We examined the association between environmental phthalates (PAEs) exposure and gut microbiota and metabolome in dementia with Lewy bodies (DLB). Background: Alongside genetic factors,…Baseline and Longitudinal NSD-ISS Staging of the PPMI Cohort
Objective: To apply biological definition and Neuronal α-Synuclein Disease Integrated Staging System (NSD-ISS) to the PPMI baseline and longitudinal dataset. Background: The NSD-ISS Working Group…A case of progressive supranuclear palsy followed by dementia with Lewy bodies
Objective: We report a case of dementia with Lewy bodies (DLB) that was diagnosed one year after the diagnosis of PSP. Background: Progressive supranuclear palsy…Cholinergic Brain Signature of Presbyvestibulopathy in Parkinson’s Disease: Exploring Central Nervous System Vestibular Mechanisms
Objective: To investigate topographic cholinergic brain differences between Parkinson's disease (PD) patients with and without presbyvestibulopathy (PVP). Background: Age-associated vestibulopathy (PVP) is commonly observed in…Visual Hallucinations and α-Synuclein Oligomers in Dementia with Lewy Bodies (DLB)
Objective: To determine whether visual hallucinations (VH) in dementia with Lewy bodies (DLB) are associated with α-synuclein oligomers. Background: It is not known whether VH…Exploring Vestibulopathy in PD: Distinguishing PD from Age-related Presbyvestibulopathy via Dynamic Gait and Balance Assessment
Objective: To investigate the influence of age-associated vestibulopathy (presbyvestibulopathy, PVP) on dynamic gait and balance in Parkinson's disease (PD) patients and elderly controls. We hypothesized…Impact of Prior Head Trauma on Parkinson’s Disease Experience
Objective: We aim to characterize the impact of prior head trauma on Parkinson’s disease (PD) related outcomes. Background: Previous head trauma is correlated with detrimental…Association between use of Furosemide and Risk of Parkinson’s disease
Objective: Main objective of study is to check the association between furosemide use and risk of Parkinson's disease (PD) in a Finnish nationwide nested case-control…Validation of Inertial Monitoring Units for Gait Assessment in Progressive Supranuclear Palsy
Objective: To evaluate the validity and precision of using inertial measurement units (IMU) for measurement of kinematics and spatial-temporal features of gait in progressive supranuclear…
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