Association Between Hypertension Timing and Clinical Variables in Parkinson’s Disease: A Retrospective Analysis
Objective: To investigate the correlation between hypertension and Parkinson's disease (PD) diagnoses' timing and clinical variables. Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder…Metabolic Progressive Subtypes in Progressive Supranuclear Palsy
Objective: To investigate disease-specific spatiotemporal progression in Progressive supranuclear palsy (PSP) patients using 18F-fluorodeoxyglucose (FDG) PET and the Subtype and Stage Inference (SuStaIn) algorithm, to…Frequency of Falls as a Presenti̇ng Symptom and Its Effect i̇n Prognosi̇s i̇n Progressi̇ve Supranuclear Palsy
Objective: We aimed to evaluate frequency of falls as a presenting symptom and its effect on prognosis in PSP patients. Background: Progressive supranuclear palsy is…18F-Florzolotau Positron Emission Tomography Imaging Correlates with Regional Brain Atrophy and Plasma Biomarkers in Tauopathy Parkinsonism Syndrome
Objective: We aim to investigate the relationship between regional 18F-florzolotau uptake and clinical severity, structural volume changes, and plasma markers in tauopathy parkinsonism syndrome. Background:…Prevalence of autonomic symptoms in Multiple System Atrophy on the background of probable RBD
Objective: To discover whether having probable rapid eye movement sleep behavior disorder (RBD) affects prevalence of particular autonomic symptoms, namely falls, constipation and urinary incontinence…Multifaceted Challenges in Multisystem Atrophy Management: Medication Sensitivity, Emotional Lability, and Increased Fall Risk
Objective: Multisystem atrophy (MSA) epitomizes a formidable quandary within neurological and geriatric disciplines, delineated by complex manifestations encompassing autonomic dysfunction, parkinsonism, and cerebellar ataxia. This…Intraepidermal Nerve Fiber Density at Baseline Associates with One-year Clinical Disease Progression in Multiple System Atrophy
Objective: In a longitudinal manner explore possible diagnostic and prognostic properties of determining intraepidermal nerve fiber density (IENFD), by means of skin punch biopsy, in…Metabolic Covariance Networks in Progressive Supranuclear Palsy Revealed by Spatial independent component analysis
Objective: The study aims to apply S-ICA to 18F-fluorodeoxyglucose (FDG) data in progressive supranuclear palsy (PSP) patients, identifing PSP-specific independent metabolic covariate networks. We also…Cytokine Profiles as Biomarkers for Neurodegenerative Diseases: An inflammatory study on Parkinson’s Disease and Tauopathies
Objective: To investigate the diagnostic and prognostic value of cytokine profiles in cerebrospinal fluid (CSF) and serum of patients with Parkinson's Disease (PD), Progressive Supranuclear…Association Between Clinical Progression in Multiple System Atrophy and Brain Volume Changes Evaluated via Deep Learning Segmentation
Objective: Assess brain volume changes in patients with multiple system atrophy (MSA) over one year. Background: Identifying disease progression biomarkers is crucial for advancing MSA…
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